Abstract.
Of the 206 patients who contracted Severe Acute Respiratory Syndrome (SARS) in Singapore five developed large artery cerebral infarctions. Four patients were critically-ill and three died. Intravenous immunoglobulin was given to three patients. An increased incidence of deep venous thrombosis and pulmonary embolism was also observed among the critically-ill patients. We believe our experience warrants an increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombotic tendency, is contemplated.
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This paper is dedicated to the five health care workers who lost their lives in the outbreak of SARS in Singapore.
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Umapathi, T., Kor, A.C., Venketasubramanian, N. et al. Large artery ischaemic stroke in severe acute respiratory syndrome (SARS). J Neurol 251, 1227–1231 (2004). https://doi.org/10.1007/s00415-004-0519-8
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DOI: https://doi.org/10.1007/s00415-004-0519-8