Skip to main content
Log in

Duration of Nil Per Os is causal in hospital length of stay following laparoscopic bariatric surgery

  • Published:
Surgical Endoscopy Aims and scope Submit manuscript

Abstract

Introduction

A recent bariatric surgical study demonstrated an inverse relationship of intraoperative hydration with the incidence of extended hospital length of stay (ehLOS: >1 postoperative hospital day). In that study, a post hoc analysis of the preoperative duration of Nil Per Os (NPO) past midnight revealed a significant dose–response association on the incidence of ehLOS, with the lowest incidence (10–12 %) predicted within the 2–5-h NPO interval. As NPO is associated with a state of compensatory dehydration, the objectives of this study were to prospectively examine the role of decreasing preoperative NPO intervals on the incidence of ehLOS in a similar bariatric surgical population and to establish causality of this association.

Methods

Following IRB approval, 168 bariatric surgeries were analyzed following institution of a revised oral water ad libitum policy until 2 h prior to surgery on the incidence of ehLOS. The role of duration of NPO on the incidence of ehLOS was assessed by logistic fit graphs and misclassification rates on the two groups. A statistical process control chart monitored the efficacy of the revised NPO guidelines.

Results

There were statistically significant, but not clinical, differences in the incidences of histories of anemia, gastroesophageal reflux disease, previous percutaneous cardiac intervention/percutaneous transluminal coronary artery angioplasty, or preoperative albumin levels between the two groups. There were no perioperative pulmonary aspirations of gastric contents in either group. Following reduction of the oral hydration interval to ≥2 h, a 13–15 % incidence of ehLOS was observed within the 2–5-h NPO interval with similar misclassification rates observed between the two groups.

Conclusions

Allowing bariatric patients access to ad libitum water for up to 2 h prior to surgery decreased the incidence of ehLOS. Comparison of the dose–response curves within the 2–5-h NPO intervals before and after introduction of the revised NPO guidelines was similar and confirms causality.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. American Society of Anesthesiologists Committee on Standards and Practice Parameters (2011) Practice guidelines for preoperative fasting and the use of pharmacologic agents to reduce the risk of pulmonary aspiration: application to healthy patients undergoing elective procedures: an updated report by the American Society of Anesthesiologists Committee on Standards and Practice Parameters. Anesthesiology 114(3):495–511

    Article  Google Scholar 

  2. Vaughan RW, Bauer S, Wise L (1975) Volume and pH of gastric juice in obese patients. Anesthesiology 43(6):686–689

    Article  CAS  PubMed  Google Scholar 

  3. Harter RL, Kelly WB, Kramer MG, Perez CE, Dzwonczyk RR (1998) A comparison of the volume and pH of gastric contents of obese and lean surgical patients. Anesth Analg 86(1):147–152

    CAS  PubMed  Google Scholar 

  4. Juvin P, Fevre G, Merouche M, Vallot T, Desmonts JM (2001) Gastric residue is not more copious in obese patients. Anesth Analg 93(6):1621–1622

    Article  CAS  PubMed  Google Scholar 

  5. Holte K, Kehlet H (2002) Compensatory fluid administration for preoperative dehydration–does it improve outcome? Acta Anaesthesiol Scand 46(9):1089–1093

    Article  CAS  PubMed  Google Scholar 

  6. Pimenta GP, de Aguilar-Nascimento JE (2014) Prolonged preoperative fasting in elective surgical patients: why should we reduce it? Am Soc Parenter Enter Nutr 29(1):22–28

    Google Scholar 

  7. Nossaman VE, Richardson WS 3rd, Wooldridge JB, Nossaman BD (2015) Role of intraoperative fluids on hospital length of stay in laparoscopic bariatric surgery: a retrospective study in 224 consecutive patients. Surg Endosc 29(10):2960–2969

    Article  PubMed  Google Scholar 

  8. Brolin RE (1996) Update: NIH consensus conference gastrointestinal surgery for severe obesity. Nutrition 12(6):403–404

    Article  CAS  PubMed  Google Scholar 

  9. Gastrointestinal surgery for severe obesity: National Institutes of Health Consensus Development Conference Statement (1992). Am J Clin Nutr 55 (2 Suppl):615S-619S

  10. Copeland KT, Checkoway H, McMichael AJ, Holbrook RH (1977) Bias due to misclassification in the estimation of relative risk. Am J Epidemiol 105(5):488–495

    Article  CAS  PubMed  Google Scholar 

  11. Lyles RH, Tang L, Superak HM, King CC, Celentano DD, Lo Y, Sobel JD (2011) Validation data-based adjustment for outcome misclassification in logistic regression: an illustration. Epidemiology 22(4):589–597

    Article  PubMed  PubMed Central  Google Scholar 

  12. Maltby JR (2006) Fasting from midnight—the history behind the dogma. Best pract Res Clin Anaesthesiol 20(3):363–378

    Article  PubMed  Google Scholar 

  13. Mendelson CL (1946) The aspiration of stomach contents into the lungs during obstetric anesthesia. Am J Obstet Gynecol 52:191–205

    Article  CAS  PubMed  Google Scholar 

  14. Fasting S, Gisvold SE (2002) Serious intraoperative problems—a five-year review of 83,844 anesthetics. Can J Anaesth 49(6):545–553

    Article  PubMed  Google Scholar 

  15. Sakai T, Planinsic RM, Quinlan JJ, Handley LJ, Kim TY, Hilmi IA (2006) The incidence and outcome of perioperative pulmonary aspiration in a university hospital: a 4-year retrospective analysis. Anesth Analg 103(4):941–947

    Article  PubMed  Google Scholar 

  16. Katz MH (2006) Study design and statistical analysis: a practical guide for clinicians. Cambridge University Press, New York

    Book  Google Scholar 

  17. de Aguilar-Nascimento JE, Dock-Nascimento DB (2010) Reducing preoperative fasting time: a trend based on evidence. World J Gastrointest Surg 2(3):57–60

    Article  PubMed  PubMed Central  Google Scholar 

  18. Awad S, Varadhan KK, Ljungqvist O, Lobo DN (2013) A meta-analysis of randomised controlled trials on preoperative oral carbohydrate treatment in elective surgery. Clin Nutr 32(1):34–44

    Article  CAS  PubMed  Google Scholar 

  19. Chen TT, Chang YJ, Ku SL, Chung KP (2010) Statistical process control as a tool for controlling operating room performance: retrospective analysis and benchmarking. J Eval Clin Pract 16(5):905–910

    Article  PubMed  Google Scholar 

  20. Matthes N, Ogunbo S, Pennington G, Wood N, Hart MK, Hart RF (2007) Statistical process control for hospitals: methodology, user education, and challenges. Qual Manag Health Care 16(3):205–214

    Article  PubMed  Google Scholar 

  21. Crenshaw JT (2011) Preoperative fasting: will the evidence ever be put into practice? Am J Nurs 111(10):38–43

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Bobby D. Nossaman.

Ethics declarations

Disclosures

Drs. Vaughn E. Nossaman, William S. Richardson, James B. Wooldridge, and Bobby D. Nossaman have no conflicts of interest or financial ties to disclose.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Nossaman, V.E., Richardson, W.S., Wooldridge, J.B. et al. Duration of Nil Per Os is causal in hospital length of stay following laparoscopic bariatric surgery. Surg Endosc 31, 1901–1905 (2017). https://doi.org/10.1007/s00464-016-5191-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00464-016-5191-4

Keywords

Navigation