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Relation between cardiovascular risk factors and nonrheumatic severe calcific aortic stenosis among patients with a three-cuspid aortic valve

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Acknowledgements

Thanks to Edward Frohlich, MD, who revised this manuscript.

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    Stewart et al.9 from the Cardiovascular Health Study reported that independent risk factors associated with CAS included elevated LDL cholesterol and LP(a), hypertension, male gender, smoking and these risk factors were similar to those observed with coronary artery disease (CAD) in the Framingham study. This new information opens up new avenue that can be targeted with statins in the medical management of CAS to prevent or retard the progression of CAS.10,11 There is no data available regarding risk factor profile in patients with CAS in Indian literature.

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