Coronary artery diseaseFrequency of Left Ventricular Thrombus in Patients With Anterior Wall Acute Myocardial Infarction Treated With Percutaneous Coronary Intervention and Dual Antiplatelet Therapy
Section snippets
Methods
We examined patients (n = 100) participating in the Autologous Stem Cell Transplantation in Acute Myocardial Infarction (ASTAMI) trial included at Ullevål University Hospital and Rikshospitalet University Hospital (Oslo, Norway).13 Patients were aged 40 to 75 years, of both genders, with acute anterior wall ST elevation myocardial infarctions and culprit lesions located in the left anterior descending coronary artery, proximal to the diagonal branch. All patients were treated successfully with
Results
LV thrombi were detected in 15 of the 100 patients within the first 3 months after the AMI: 6 of the patients allocated to the mBMC group and 9 of those allocated to the control group (p = 0.58 for the difference between the groups). One of the patients experienced a minor cerebral stroke. As visualized in Figure 1, most of the LV thrombus formation was detected within the first week after acute PCI. LV thrombi were diagnosed by echocardiography in 13 patients and by magnetic resonance imaging
Discussion
Our study of selected patients with acute anterior wall ST elevation myocardial infarctions treated successfully with PCI and intensive antiplatelet treatment confirms that LV thrombus remains a frequent finding. Although patients with the most extensive myocardial infarcts with cardiogenic shock were excluded, LV thrombi were detected in 15 of 100 patients. In recent years, acute PCI has been the preferred revascularization method in patients with ST elevation myocardial infarctions, with an
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