Original articleClinical endoscopyAgile patency system eliminates risk of capsule retention in patients with known intestinal strictures who undergo capsule endoscopy
Section snippets
Patients and methods
Patients over 18 years of age with evidence of an intestinal stricture as detected by radiographic means, either CT or SBFT, were eligible for inclusion in this international multicenter study. Subjects with pacemakers or other implanted electromedical devices, swallowing disorders, or fewer than 2 bowel movements per week and pregnant women were excluded. The study was approved by the local ethics committee or institutional review board at each participating center, and written informed
Results
A total of 106 patients were enrolled in the study. The basic demographic characteristics of the study population are shown in Table 1. Patient characteristics including the presence of known Crohn's disease and symptoms were recorded at enrollment.
Of the 106 subjects enrolled, 59 (56%) excreted the Agile patency capsule intact and thereby demonstrated functional patency of the small intestine (Fig. 4). Forty-seven capsules (44%) were excreted in a deformed state. No capsules were found to have
Discussion
CE has been shown to be an extremely important tool in visualizing the small intestinal mucosa. Although it is generally considered a very safe procedure, there is a small chance of capsule retention within the small bowel. Among these patients with capsule retention, a very small minority may have a blockage of the small bowel requiring surgical intervention.10 Screening of patients before CE with SBFT has been shown to be inaccurate for predicting capsule retention. This study shows that the
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Cited by (0)
See CME section; p. 932.