Chest
Clinical Investigations: COPDPerception of Fatigue and Quality of Life in Patients With COPD
Section snippets
Sample
A convenience sample of 41 patients with stable COPD (FEV1 = 1.08 L [±0.55], FEV1, percent predicted = 35.8% [±16.6]) from two sites participated in the study. Based on Cohen's standard approach for correlation,22 anticipating a moderate effect size, the sample size is adequate to achieve the purpose of evaluating universal similarities of fatigue in this population from two international sites. The study was approved by the Human Subjects Review Board at the University of California, Davis and
RESULTS
Forty-one patients (28 male, 13 female) with moderate to severe COPD participated in the study (Table 1). There were no significant differences between the Dutch and American groups in each dimension of fatigue (Table 2). American patients showed a trend toward lower FVC, percent predicted (p = 0.055) than the Dutch patients but not with any other pulmonary function values. The American patients showed higher scores, and therefore, greater impairment in the activity subscale of the SGRQ (p <
DISCUSSION
Among the possible dimensions of fatigue in COPD, we measured five in the present study in the MFI-20: general or overall fatigue, two physical dimensions, physical fatigue and reduction in activity, and two cognitive dimensions, reduction in motivation and mental fatigue. Data from the present study were considered as regards the expected relationships between fatigue and the outcome measures. We show three major findings. Increased fatigue is associated with (1) an increase in the severity of
REFERENCES (42)
Fatigue: towards an analysis and a unified definition
Med Hypotheses
(1980)The epidemiology of self-perceived fatigue among adults
Prev Med
(1986)- et al.
The Multidimensional Fatigue Inventory (MFI) psychometric qualities of an instrument to assess fatigue
J Psychosom Med
(1995) General thoracic surgery: technique of lung volume reduction
J Thorac Cardiovasc Surg
(1995)Measuring depression: the CES-D Scale
- et al.
Exercise limitation and pulmonary rehabilitation in chronic obstructive pulmonary disease
Mayo Clin Proc
(1992) Self reported fatigue in rheumatoid arthritis: a pilot study
Arthritis Care Res
(1990)- et al.
Correlates of fatigue in older adults with rheumatoid arthritis
Nurs Res
(1993) - et al.
Fatigue in primary care: prevalence, psychiatric comorbidity, illness behavior, and outcome
J Gen Intern Med
(1992) - et al.
Correlates of fatigue in people with breast or lung cancer
Oncol Nurs Forum
(1991)
Fatigue and depression in the patient in the intensive care unit
Prim Care
Patients’ descriptions of the influence of tiredness and weakness on self-care abilities
Can Nurs
Validity and reliability of a quality of life instrument: the chronic respiratory disease questionnaire
Clin Nurs Res
A note on the significance of fatigue
Psychosom Med
Validity and reliability of the St. George’s respiratory questionnaire after adaptation to a different language and culture: the Spanish example
Eur Respir J
Determinants of health-related quality of life in patients with chronic obstructive pulmonary disease
Thorax
Quality of life in elderly patients with chronic nonspecific lung disease seen in family practice
Chest
Quality of life in patients with chronic obstructive pulmonary disease and severe hypoxaemia
Thorax
Life quality of patients with chronic obstructive pulmonary disease
Arch Intern Med
A measure of quality of life for clinical trials in chronic lung disease
Thorax
Quality of life and its predictors in patients with mild hypoxemia and chronic obstructive pulmonary disease
Arch Intern Med
Cited by (167)
Sleep disorders in elderly population suffering from TB and respiratory diseases
2022, Indian Journal of TuberculosisCharacterisation of fatigue and its substantial impact on health status in a large cohort of patients with chronic pulmonary aspergillosis (CPA)
2016, Respiratory MedicineCitation Excerpt :Indeed, these findings reflect the clinical importance of fatigue as a novel target for therapeutic intervention for two reasons. Firstly, fatigue has been reported to be one of the most inhibiting symptoms preventing physical activity in chronic respiratory conditions such as COPD [12,30]. Regular physical activity in COPD is associated with reduced hospital admission and mortality [44].
Long-term survival after cardiac surgery in patients with chronic obstructive pulmonary disease
2016, American Journal of Critical CareMeasuring individual true change with PROMIS using IRT-based plausible values
2023, Quality of Life ResearchThe effects of COVID-19 on respiratory muscle performance: making the case for respiratory muscle testing and training
2022, European Respiratory Review