Human granulocytic anaplasmosis during pregnancy: case series and literature review

Clin Infect Dis. 2007 Sep 1;45(5):589-93. doi: 10.1086/520659. Epub 2007 Jul 30.

Abstract

We describe the clinical and laboratory manifestations and pregnancy outcomes of 6 women who received a diagnosis of human granulocytic ehrlichiosis during pregnancy. Human granulocytic ehrlichiosis did not seem to present in a fulminant fashion, and all treated patients had excellent responses to rifampin or doxycycline therapy. Perinatal transmission was documented in 1 neonate, who responded well to treatment. There do not appear to be any long-term adverse sequelae in children born from these pregnancies (mean follow-up duration, 21 months).

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Anaplasma phagocytophilum / drug effects
  • Anaplasma phagocytophilum / pathogenicity
  • Anti-Bacterial Agents / therapeutic use*
  • Doxycycline / therapeutic use*
  • Ehrlichiosis / complications*
  • Ehrlichiosis / drug therapy
  • Ehrlichiosis / transmission
  • Female
  • Follow-Up Studies
  • Humans
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical*
  • New York
  • Pregnancy
  • Pregnancy Complications, Infectious / drug therapy*
  • Pregnancy Outcome
  • Rifampin / therapeutic use*

Substances

  • Anti-Bacterial Agents
  • Doxycycline
  • Rifampin