Electrophysiologic properties of propoxyphene and norpropoxyphene in canine cardiac conducting tissues in vitro and in vivo

Toxicol Appl Pharmacol. 1979 Jan;47(1):123-33. doi: 10.1016/0041-008x(79)90079-6.
No abstract available

MeSH terms

  • Action Potentials / drug effects
  • Anesthetics, Local
  • Animals
  • Bundle of His / drug effects
  • Dealkylation
  • Dextropropoxyphene / pharmacology*
  • Dogs
  • Electrocardiography
  • Female
  • Guinea Pigs
  • Heart Conduction System / drug effects*
  • Heart Rate / drug effects
  • In Vitro Techniques
  • Kinetics
  • Male
  • Myocardial Contraction / drug effects
  • Purkinje Fibers / drug effects
  • Rats

Substances

  • Anesthetics, Local
  • Dextropropoxyphene