Metabolic syndrome associated with primary biliary cirrhosis

A Floreani, N Cazzagon, I Franceschet… - Journal of clinical …, 2015 - journals.lww.com
Aim: To assess the influence of metabolic syndrome (MS) on response to ursodeoxycholic
acid (UDCA) and the survival in PBC patients. Methods: The historical database (1975 to
2011) comprising consecutively enrolled PBC patients with a mean follow-up of 123 months
(range, 12 to 425 mo) was used. All patients were treated with UDCA (15 mg/kg/d).
Responders to UDCA were defined as patients achieving at least a 40% drop in their
alkaline phosphatase levels after 1 year. MS was defined according to the American Heart …