User profiles for Adam J. Brown

Adam J. Brown

- Verified email at monash.edu - Cited by 7688

Adam J Brown

- Verified email at sheffield.ac.uk - Cited by 350

Imaging atherosclerosis

…, MR Dweck, NR Evans, RAP Takx, AJ Brown… - Circulation …, 2016 - Am Heart Assoc
Advances in atherosclerosis imaging technology and research have provided a range of
diagnostic tools to characterize high-risk plaque in vivo; however, these important vascular …

Role of biomechanical forces in the natural history of coronary atherosclerosis

AJ Brown, Z Teng, PC Evans, JH Gillard… - Nature reviews …, 2016 - nature.com
Atherosclerosis remains a major cause of morbidity and mortality worldwide, and a
thorough understanding of the underlying pathophysiological mechanisms is crucial for the …

Remote ischemic preconditioning improves outcome at 6 years after elective percutaneous coronary intervention: the CRISP stent trial long-term follow-up

WR Davies, AJ Brown, W Watson… - Circulation …, 2013 - Am Heart Assoc
Background— Postprocedural myocardial infarction (type 4a) has been shown to be an
adverse prognostic indicator after elective percutaneous coronary intervention (PCI). The …

Computed tomographic coronary angiography–derived plaque characteristics predict major adverse cardiovascular events: a systematic review and meta-analysis

…, DT Wong, S Seneviratne, AJ Brown - Circulation …, 2018 - Am Heart Assoc
Background— Computed tomographic coronary angiography is a noninvasive imaging modality
that permits identification and characterization of coronary plaques. Despite consensus …

Association of epicardial adipose tissue and high‐risk plaque characteristics: a systematic review and meta‐analysis

N Nerlekar, AJ Brown, RG Muthalaly… - Journal of the …, 2017 - Am Heart Assoc
Background Epicardial adipose tissue ( EAT ) is hypothesized to alter atherosclerotic plaque
composition, with potential development of high‐risk plaque ( HRP ). EAT can be measured …

[HTML][HTML] Material properties of components in human carotid atherosclerotic plaques: a uniaxial extension study

…, J Feng, J Yuan, Q Lu, MPF Sutcliffe, AJ Brown… - Acta biomaterialia, 2014 - Elsevier
Computational modelling to calculate the mechanical loading within atherosclerotic plaques
has been shown to be complementary to defining anatomical plaque features in …

Smart watches for heart rate assessment in atrial arrhythmias

AN Koshy, JK Sajeev, N Nerlekar, AJ Brown… - International journal of …, 2018 - Elsevier
Background Despite studies demonstrating the accuracy of smart watches (SW) and
wearable heart rate (HR) monitors in sinus rhythm, no data exists regarding their utility in …

High wall shear stress and high-risk plaque: an emerging concept

P Eshtehardi, AJ Brown, A Bhargava… - The international journal …, 2017 - Springer
In recent years, there has been a significant effort to identify high-risk plaques in vivo prior to
acute events. While number of imaging modalities have been developed to identify …

Direct comparison of virtual-histology intravascular ultrasound and optical coherence tomography imaging for identification of thin-cap fibroatheroma

AJ Brown, DR Obaid, C Costopoulos… - Circulation …, 2015 - Am Heart Assoc
Background— Although rupture of thin-cap fibroatheroma (TCFA) underlies most myocardial
infarctions, reliable TCFA identification remains challenging. Virtual-histology intravascular …

Coronary plaque structural stress is associated with plaque composition and subtype and higher in acute coronary syndrome: the BEACON I (Biomechanical …

Z Teng, AJ Brown, PA Calvert, RA Parker… - Circulation …, 2014 - Am Heart Assoc
Background— Atherosclerotic plaques underlying most myocardial infarctions have thin
fibrous caps and large necrotic cores; however, these features alone do not reliably identify …