Incidence of ARDS in an adult population of northeast Ohio

AC Arroliga, ZW Ghamra, AP Trepichio, PP Trepichio… - Chest, 2002 - Elsevier
Study objectives To assess the incidence of the ARDS in a well-defined adult population.
Design Kaiser Permanente of northeast Ohio, a health maintenance organization, uses the …

Brain tissue sodium is a ticking clock telling time after arterial occlusion in rat focal cerebral ischemia

Y Wang, W Hu, AD Perez-Trepichio, TC Ng, AJ Furlan… - Stroke, 2000 - Am Heart Assoc
Background and Purpose—Many patients with acute stroke are excluded from receiving
thrombolysis agents within the necessary time limit (3 or 6 hours from stroke onset) because …

Cortical NOS inhibition raises the lower limit of cerebral blood flow-arterial pressure autoregulation

…, D Chyatte, AD Perez-Trepichio - American Journal …, 1999 - journals.physiology.org
The maintenance of constant cerebral blood flow (CBF) as arterial blood pressure is reduced,
commonly referred to as CBF-pressure autoregulation, is typically characterized by a …

Variability in the magnitude of the cerebral blood flow response and the shape of the cerebral blood flow: pressure autoregulation curve during hypotension in normal …

…, Y Qu, KA Easley, AD Perez-Trepichio - The Journal of the …, 2002 - pubs.asahq.org
Background The maintenance of constant cerebral blood flow (CBF) as mean cerebral
perfusion pressure (CPP) varies is commonly referred to as CBF-pressure autoregulation. The …

Sensitivity of magnetic resonance diffusion-weighted imaging and regional relationship between the apparent diffusion coefficient and cerebral blood flow in rat focal …

AD Perez-Trepichio, M Xue, TC Ng, AW Majors… - Stroke, 1995 - Am Heart Assoc
Background and Purpose Magnetic resonance (MR) diffusion-weighted imaging (DWI), a
noninvasive procedure, may play an important role in detecting and accurately localizing the …

Hydroxyethyl starch 200/0.5 reduces infarct volume after embolic stroke in rats.

AD Perez-Trepichio, AJ Furlan, JR Little, SC Jones - Stroke, 1992 - Am Heart Assoc
We evaluated isovolumic hemodilution with hydroxyethyl starch 200/0.5 in a rat model of
focal cerebral ischemia. This compound avoids the unfavorable viscosity and erythrocyte …

Nitric Oxide Synthase Inhibition Depresses the Height of the Cerebral Blood Flow–Pressure Autoregulation Curve during Moderate Hypotension

…, AJ Furlan, AD Perez-Trepichio - Journal of Cerebral …, 2003 - journals.sagepub.com
Variations in the height of the CBF response to hypotension have been described recently in
normal animals. The authors evaluated the effects of nitric oxide synthase (NOS) inhibition …

Cardiovascular changes during focal cerebral ischemia in rats.

AD Perez-Trepichio, JL Williams, CH Block, SC Jones - Stroke, 1993 - Am Heart Assoc
Recent studies have suggested that cerebral infarction influences autonomic activity and may
contribute to sudden death. The goal of this study was to examine effects of focal cerebral …

Directed sampling for electrolyte analysis and water content of micro-punch samples shows large differences between normal and ischemic rat brain cortex

W Hu, A Kharlamov, Y Wang, AD Perez-Trepichio… - Brain research, 2000 - Elsevier
Changes in sodium, potassium, and water content in brain tissue are important in the progression
of pathology that follows ischemic stroke. Determining these parameters regionally in …

Quality assessment in the medical intensive care unit: Continued evolution of a data model

ED Sivak, A Perez-Trepichio - American Journal of Medical …, 1992 - journals.lww.com
Quality assessment and assurance activities in the intensive care unit are complex processes
that begin with the definition of the scope of services delivered in the unit with further …