Several commonly prescribed antiepileptic drugs (AEDs)—including phenobarbital, phenytoin,
and carbamazepine—stimulate the synthesis of a broad range of monooxygenase and …

Adults taking antiepileptic drugs (AEDs) have an augmented risk for osteopenia and
osteoporosis because of abnormalities of bone metabolism associated with AEDs. The increased …

PURPOSE OF REVIEW The classification of seizures, epilepsies, and epilepsy syndromes
creates a framework for clinicians, researchers, and patients and their families. This …

Antiepileptic drugs, particularly cytochrome P450 enzyme inducers, are associated with
disorders of bone metabolism. We studied premenopausal women with epilepsy receiving …

A growing body of literature indicates an association between antiepileptic drugs (AEDs)
and bone disease, including histologic, radiographic, and biochemical evidence. The AEDs …

Objective Somatic variants are a recognized cause of epilepsy‐associated focal malformations
of cortical development (MCD). We hypothesized that somatic variants may underlie a …

Antiepileptic drugs (AEDs) were first associated with disorders of bone in both adults and
children in the late 1960s. The most severe manifestations of these disorders are osteopenia/…

Antiepileptic drugs (AEDs) are associated with bone disease. Early reports found rickets in
children and osteomalacia in adults, but those reports were primarily in institutionalized …

Women with epilepsy are believed to be at risk for sexual dysfunction. Disorders of sexual
desire and sexual arousal, including dyspareunia, vaginismus, and lack of lubrication, affect …

Importance There is limited information on infant drug exposure via breastfeeding by
mothers who are receiving antiepileptic drug therapy. Objective To provide direct, objective …