[PDF][PDF] Diabetic foot infections: a comprehensive overview.

…, S Caputo, G Tinelli, F Zaccardi, A Flex… - European Review for …, 2019 - researchgate.net
Diabetic foot ulcers (DFUs), a micro-vascular complication, are associated with a substantial
increase in morbidity and mortality. DFUs are a complicated mixture of neuropathy, …

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

…, GT Jones, T Mueller, A Gottsäter, A Flex… - Nature, 2008 - nature.com
Smoking is a leading cause of preventable death, causing about 5 million premature deaths
worldwide each year 1 , 2 . Evidence for genetic influence on smoking behaviour and …

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

…, N Sakalihasan, K Kostulas, A Gottsäter, A Flex… - Nature …, 2008 - nature.com
Recently, two common sequence variants on 9p21, tagged by rs10757278-G and rs10811661-T,
were reported to be associated with coronary artery disease (CAD) 1, 2, 3, 4 and type 2 …

[PDF][PDF] Something more to say about calcium homeostasis: the role of vitamin K2 in vascular calcification and osteoporosis.

…, TA Di Rienzo, MA Zocco, A Flex… - European Review for …, 2013 - researchgate.net
DISCUSSION: Vitamin K2 is essential for the function of several proteins, involved in the
maintenance of the normal structure of arterial wall, osteoarticular system, teeth, and for the …

[HTML][HTML] Dietary risk factors and eating behaviors in peripheral arterial disease (PAD)

…, PJ Dimuzio, A Gasbarrini, M Massetti, A Flex - International Journal of …, 2022 - mdpi.com
Dietary risk factors play a fundamental role in the prevention and progression of atherosclerosis
and PAD (Peripheral Arterial Disease). The impact of nutrition, however, defined as the …

Proinflammatory genetic profiles in subjects with history of ischemic stroke

A Flex, E Gaetani, P Papaleo, G Straface, AS Proia… - Stroke, 2004 - Am Heart Assoc
Background and Purpose— Proinflammatory genetic profiles, resulting from the combination
of single nucleotide polymorphisms in genes encoding inflammatory molecules, may …

Sonic hedgehog regulates angiogenesis and myogenesis during post‐natal skeletal muscle regeneration

G Straface, T Aprahamian, A Flex… - Journal of cellular …, 2009 - Wiley Online Library
Sonic hedgehog (Shh) is a morphogen‐regulating crucial epithelial‐mesenchymal interactions
during embryonic development, but its signalling pathway is considered generally silent …

High-mobility group box-1 protein promotes angiogenesis after peripheral ischemia in diabetic mice through a VEGF-dependent mechanism

…, K Egashira, G De Angelis, G Ghirlanda, A Flex - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE High-mobility group box-1 (HMGB1) protein is a nuclear DNA-binding protein
released from necrotic cells, inducing inflammatory responses and promoting tissue repair …

Selective activation of peroxisome proliferator–activated receptor (PPAR) α and PPARγ induces neoangiogenesis through a vascular endothelial growth factor …

F Biscetti, E Gaetani, A Flex, T Aprahamian… - …, 2008 - Am Diabetes Assoc
OBJECTIVE—Peroxisome proliferator–activated receptors (PPARs) are therapeutic targets
for fibrates and thiazolidinediones, which are commonly used to ameliorate hyperlipidemia …

Assessment of neurological manifestations in hospitalized patients with COVID‐19

…, G Ferrone, R Festa, MC Fiore, A Flex… - European journal of …, 2020 - Wiley Online Library
Background and purpose The objective of this study was to assess the neurological
manifestations in a series of consecutive severe acute respiratory syndrome coronavirus 2 (SARS‐…