Trial of early aggressive therapy in polyarticular juvenile idiopathic arthritis
…, KM O'Neil, AS Zeft, IS Szer, S Ringold… - Arthritis & …, 2012 - Wiley Online Library
Objective To determine whether aggressive treatment initiated early in the course of rheumatoid
factor (RF)–positive or RF‐negative polyarticular juvenile idiopathic arthritis (JIA) can …
factor (RF)–positive or RF‐negative polyarticular juvenile idiopathic arthritis (JIA) can …
Classification, presentation, and initial treatment of Wegener's granulomatosis in childhood
…, PJ Hashkes, G Higgins, AS Zeft… - … : Official Journal of …, 2009 - Wiley Online Library
Objective To compare the criteria for Wegener's granulomatosis (WG) of the American
College of Rheumatology (ACR) with those of the European League Against Rheumatism/…
College of Rheumatology (ACR) with those of the European League Against Rheumatism/…
HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis
…, S Özen, S Prahalad, AS Zeft… - Proceedings of the …, 2015 - National Acad Sciences
Systemic juvenile idiopathic arthritis (sJIA) is an often severe, potentially life-threatening
childhood inflammatory disease, the pathophysiology of which is poorly understood. To …
childhood inflammatory disease, the pathophysiology of which is poorly understood. To …
Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications
Objectives Juvenile idiopathic arthritis (JIA) is a heterogeneous group of conditions unified
by the presence of chronic childhood arthritis without an identifiable cause. Systemic JIA (sJIA…
by the presence of chronic childhood arthritis without an identifiable cause. Systemic JIA (sJIA…
Clinically inactive disease in a cohort of children with new-onset polyarticular juvenile idiopathic arthritis treated with early aggressive therapy: time to achievement …
…, KM O'Neil, AS Zeft, IS Szer, S Ringold… - The Journal of …, 2014 - jrheum.org
Objective. To determine the elapsed time while receiving aggressive therapy to the first
observation of clinically inactive disease (CID), total duration of CID and potential predictors of …
observation of clinically inactive disease (CID), total duration of CID and potential predictors of …
Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic arthritis
S Prahalad, S Hansen, A Whiting… - … : Official Journal of …, 2009 - Wiley Online Library
Objective Subtypes of juvenile idiopathic arthritis (JIA) share phenotypic features with other
autoimmune disorders. We investigated several genetic variants associated with rheumatoid …
autoimmune disorders. We investigated several genetic variants associated with rheumatoid …
Quantification of the familial contribution to juvenile idiopathic arthritis
S Prahalad, AS Zeft, R Pimentel, B Clifford… - Arthritis & …, 2010 - Wiley Online Library
Objective We previously demonstrated that there is familial aggregation of juvenile idiopathic
arthritis (JIA). Using a large JIA cohort, we sought to identify additional clusters of JIA cases …
arthritis (JIA). Using a large JIA cohort, we sought to identify additional clusters of JIA cases …
[HTML][HTML] Takayasu arteritis in the pediatric population: a contemporary United States-based single center cohort
HS Szugye, AS Zeft, SJ Spalding - Pediatric Rheumatology, 2014 - Springer
Background Takayasu Arteritis is an idiopathic, chronic, large vessel vasculitis involving the
aorta and its primary branches. Few studies have been done in pediatric patients to date …
aorta and its primary branches. Few studies have been done in pediatric patients to date …
IL1RN Variation Influences Both Disease Susceptibility and Response to Recombinant Human Interleukin‐1 Receptor Antagonist Therapy in Systemic Juvenile …
Objective To determine whether systemic juvenile idiopathic arthritis (JIA) susceptibility loci
that were identified by candidate gene studies demonstrate association with systemic JIA in …
that were identified by candidate gene studies demonstrate association with systemic JIA in …
Hierarchy of risk of childhood‐onset rheumatoid arthritis conferred by HLA–DRB1 alleles encoding the shared epitope
…, A Reed, JL Park, ED Mellins, AS Zeft… - Arthritis & …, 2012 - Wiley Online Library
Objective Associations between shared epitope (SE)–encoding HLA–DRB1 alleles and
rheumatoid arthritis (RA) are well established. However, only a limited number of studies have …
rheumatoid arthritis (RA) are well established. However, only a limited number of studies have …