Background Protection afforded from prior disease among patients with coronavirus
disease 2019 (COVID-19) infection is unknown. If infection provides substantial long-lasting …

… Reddy contributed substantially to data analysis and interpretation and the writing of the
article. … Can J Anaesth 2020; 67:369–376 … Am J Epidemiol 1998; 148:631–642 …

In hospitalized patients, elevated serum lactate levels are both a marker of risk and a target
of therapy. The authors describe the mechanisms underlying lactate elevations, note the …

Background Initial fluid resuscitation volume for sepsis is controversial, particularly in patients
at high baseline risk for complications. This study was designed to assess the association …

OBJECTIVES: To formulate new “Choosing Wisely” for Critical Care recommendations that
identify best practices to avoid waste and promote value while providing critical care. DATA …

Nrf2 is essential to antioxidant response element (ARE)-mediated host defense. Sulforaphane
(SFN) is a phytochemical antioxidant known to affect multiple cellular targets including …

PURPOSE: There are little data regarding the discontinuation of vasoactive medications in
patients recovering from septic shock. We designed this retrospective cohort study to evaluate …

The home test kits for detecting SARS-CoV-2 infection with Food and Drug Administration
emergency use authorization primarily use either isothermal nucleic acid amplification or …

Study Objective To identify risk factors associated with bleeding in patients who received
alteplase for pulmonary embolism ( PE ), with a specific focus on risk factors available to the …

Study Objectives Patients with septic shock often require vasoactive agents for hemodynamic
support; however, the optimal approach to discontinuing these agents once patients reach …