To more fully characterize the available evidence supporting the recommendations, the
AASLD Practice Guidelines Committee has adopted the classification used by the Grading of …

Peroxidative decomposition of cellular membrane lipids is a postulated mechanism of
hepatocellular injury in parenchymal iron overload. In the present study, we looked for direct …

BACKGROUND Hereditary hemochromatosis (HH) is the most common, identified, genetic
disorder in the Caucasian population. Although its geographic distribution is worldwide, it is …

… Anthony Tavill provided guidance in the writing and editing of the article. … Northern European
ancestry (Z and S alleles), and some Southern European ancestry (S allele). Although it has …

This article addresses the role of the liver in normal glucose homeostasis and discusses a
variety of liver conditions associated with abnormal glucose homeostasis. This association …

Hepatic iron concentration has consistently been observed as being directly correlated with
the response to interferon therapy in chronic hepatitis C virus (HCV). We therefore …

Patients with chronic hepatitis C and low serum and hepatic iron stores may have an improved
response to interferon (IFN). We tested whether iron reduction before and during IFN …

Abnormalities in protein and energy metabolism occur frequently in chronic liver disease
with resultant malnutrition. Since many of the complications of liver disease (such as …

Connective tissue diseases such as systemic lupus erythematosus (SLE), rheumatoid
arthritis, Sjögren's syndrome, and scleroderma are systemic disorders that may have an …

We examined the effects of chronic dietary iron overload on hepatic mitochondrial oxidative
metabolism. Experimental iron overload was produced by feeding rats a chow diet …