Exploitation of protein kinase C: a useful target for cancer therapy

AS Ali, S Ali, BF El-Rayes, PA Philip, FH Sarkar - Cancer treatment reviews, 2009 - Elsevier
Protein kinase C is a family of serine/threonine kinases. The PKC family is made up of at
least 12 isozymes, which have a role in cell proliferation, differentiation, angiogenesis, and …

3, 3′‐diindolylmethane enhances taxotere‐induced growth inhibition of breast cancer cells through downregulation of FoxM1

A Ahmad, S Ali, Z Wang, AS Ali, S Sethi… - … journal of cancer, 2011 - Wiley Online Library
Emerging evidence suggests that the transcription factor Forkhead Box M1 (FoxM1) is
associated with aggressive human carcinomas, including breast cancer. Because elevated …

A novel copper complex of 3‐benzoyl‐α methyl benzene acetic acid with antitumor activity mediated via cyclooxygenase pathway

…, S Adsule, AS Ali, S Banerjee, S Ali… - … journal of cancer, 2007 - Wiley Online Library
Pancreatic cancer (PC) is characterized as one of the deadliest malignancies and its treatment
is a great challenge to clinical oncologists. Expression of COX‐2 is detectable in 75% of …

The role of cancer stem cells and miRNAs in defining the complexities of brain metastasis

AS Ali, A Ahmad, S Ali, B Bao, PA Philip… - Journal of cellular …, 2013 - Wiley Online Library
Researchers and clinicians have been challenged with the development of therapies for the
treatment of cancer patients whose tumors metastasized to the brain. Among the most lethal …

MicroRNAs in breast cancer research: progress and promise

A Ahmed, AS Ali, S Ali, A Ahmad, PA Philip… - … Cancer Metastasis and …, 2013 - Springer
Over the years, remarkable progress has been made in regards to our understanding of breast
cancer biology and consequently the development of novel treatments. One idea that has …

MicroRNAs in cancer invasion and metastasis

AS Ali, S Ali, A Ahmad, PA Philip, FH Sarkar - MicroRNAs in Cancer …, 2011 - Springer
The field of cancer research has received invaluable gifts over the last few decades through
novel innovations in molecular understanding and drug development. One area that is …

[HTML][HTML] The role of urgent care centers in headache management: a quality improvement project

…, J Guiracocha, A Ehrlich, FA Khan, AS Ali… - BMC Health Services …, 2022 - Springer
Background Patients with headache often seek urgent medical care to treat pain and associated
symptoms that do not respond to therapeutic options at home. Urgent Cares (UCs) may …

Lipid nanocarrier of selegiline augmented anti-Parkinson's effect via P-gp modulation using quercetin

…, MU Ashhar, FF Qizilibash, PK Sahoo, A Ali… - International Journal of …, 2021 - Elsevier
In the present study, SEL was loaded in a lipid nanocarrier (LNC) formulation with a P-gp
pump inhibitor ie, Quercetin (QUR) for improving the bioavailability of the SEL in the brain via …

Amelioration of oxidative stress utilizing nanoemulsion loaded with bromocriptine and glutathione for the management of Parkinson's disease

…, PK Sahoo, K Nigam, S Dang, J Ali, S Baboota - International Journal of …, 2022 - Elsevier
Parkinson's disease (PD) is triggered by the formation of free radicals in dopaminergic neurons,
which results in oxidative stress-induced neurodegeneration. The objective of the work …

[HTML][HTML] Thymoquinone-enriched naringenin-loaded nanostructured lipid carrier for brain delivery via nasal route: in vitro prospect and in vivo therapeutic efficacy for …

…, MU Ashhar, A Zafar, Z Qamar, Annu, J Ali, S Baboota… - Pharmaceutics, 2022 - mdpi.com
In the current research, a thymoquinone-enriched naringenin (NGN)-loaded nanostructured
lipid carrier (NLC) was developed and delivered via the nasal route for depression. …