Background & Aims Hepatocellular carcinoma (HCC), the most common primary liver cancer,
remains a deadly cancer, with an incidence that has tripled in the United States since 1980…

Importance Colorectal cancer is a leading cause of cancer-related death, and nearly 70% of
patients with this cancer have unresectable colorectal cancer liver metastases (CRLMs). …

Background: Advanced hepatocellular cancer (HCC) is an incurable disease with limited
options for systemic treatment. Sorafenib was approved for advanced HCC based on trials in …

Background Cholangiocarcinoma is an aggressive malignancy with few available studies
assessing incidence and mortality. In this study, we aim to investigate trends of incidence and …

Introduction Prognostication in cancer is challenging and inaccurate. C-Reactive Protein (CRP),
a cheap and sensitive marker of inflammation may help. This study investigated the …

Systematic studies evaluating clinical benefit of tumor genomic profiling are lacking. We
conducted a prospective study in 250 patients with select solid tumors at the Cleveland Clinic. …

. ABSTRACT Physicians can do a better job of palliating symptoms and improving the quality
of life of cancer patients if they understand the principles of symptom management. We …

Neutrophil extracellular traps (NETs), a web-like structure of cytosolic and granule proteins
assembled on decondensed chromatin, kill pathogens and cause tissue damage in diseases. …

Introduction Cancer-related anorexia is traditionally considered part of a complex but ill-defined
anorexia–cachexia syndrome in which anorexia is intimately associated with other …

CONTEXT: Cancer pain is debilitating and has multidimensional consequences. It can be
treated adequately in up to 90% of patients by following pain management guidelines. …