Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation

…, R Rana, JLS Sauver, JF Lymp, B Afessa… - Critical care …, 2004 - journals.lww.com
Objective: Although ventilation with small tidal volumes is recommended in patients with
established acute lung injury, most others receive highly variable tidal volume aimed in part at …

Silver-coated endotracheal tubes and incidence of ventilator-associated pneumonia: the NASCENT randomized trial

MH Kollef, B Afessa, A Anzueto, C Veremakis, KM Kerr… - Jama, 2008 - jamanetwork.com
Context Ventilator-associated pneumonia (VAP) causes substantial morbidity. A silver-coated
endotracheal tube has been designed to reduce VAP incidence by preventing bacterial …

The importance of fluid management in acute lung injury secondary to septic shock

…, JA Doherty, RM Reichley, O Gajic, B Afessa… - Chest, 2009 - Elsevier
Background Recent studies have suggested that early goal-directed resuscitation of patients
with septic shock and conservative fluid management of patients with acute lung injury (ALI) …

Transfusion-related acute lung injury in the critically ill: prospective nested case-control study

…, M Malinchoc, SR DeGoey, B Afessa… - American journal of …, 2007 - atsjournals.org
Rationale: Acute lung injury (ALI) that develops 6 hours after transfusion (TRALI) is the
leading cause of transfusion-related mortality. Several transfusion characteristics have been …

Fresh-frozen plasma and platelet transfusions are associated with development of acute lung injury in critically ill medical patients

H Khan, J Belsher, M Yilmaz, B Afessa, JL Winters… - Chest, 2007 - Elsevier
Background Transfusion has long been identified as a risk factor for acute lung injury (ALI)/ARDS.
No study has formally evaluated the transfusion of specific blood products as a risk …

Clinical spectrum, frequency, and significance of myocardial dysfunction in severe sepsis and septic shock

JN Pulido, B Afessa, M Masaki, T Yuasa… - Mayo Clinic …, 2012 - Elsevier
Objective To determine the frequency and spectrum of myocardial dysfunction in patients with
severe sepsis and septic shock using transthoracic echocardiography and to evaluate the …

[HTML][HTML] Intensive care of the cancer patient: recent achievements and remaining challenges

…, M Darmon, D Benoit, S Pastores, B Afessa - Annals of intensive …, 2011 - Springer
A few decades have passed since intensive care unit (ICU) beds have been available for
critically ill patients with cancer. Although the initial reports showed dismal prognosis, recent …

[HTML][HTML] Thrombocytopenia in adult patients with sepsis: incidence, risk factors, and its association with clinical outcome

C Venkata, R Kashyap, JC Farmer, B Afessa - Journal of intensive care, 2013 - Springer
Background Sepsis is a major risk factor for the development of thrombocytopenia, but few
studies have specifically evaluated prognostic importance of thrombocytopenia in patients …

Systemic inflammatory response syndrome, organ failure, and outcome in critically ill obstetric patients treated in an ICU

B Afessa, B Green, I Delke, K Koch - Chest, 2001 - Elsevier
Study objectives To determine the incidence of systemic inflammatory response syndrome (SIRS)
and organ failure and to describe the outcomes in critically ill obstetric patients who …

Severity of illness scoring systems in the intensive care unit

MT Keegan, O Gajic, B Afessa - Critical care medicine, 2011 - journals.lww.com
Objective: Adult intensive care unit prognostic models have been used for predicting patient
outcome for three decades. The goal of this review is to describe the different versions of the …