Azithromycin has a well-characterized bacteriostatic activity. However, it also has a robust
immunomodulatory effect that has proven beneficial in a variety of chronic illnesses. This effect …

Developmental transcription programs are epigenetically regulated by the competing actions
of polycomb and trithorax (TrxG) protein complexes, which repress and activate genes, …

Objectives Sickle cell disease‐related pulmonary hypertension (SCD‐PH) is a complex
disorder with multifactorial contributory mechanisms. Previous trials have evaluated the efficacy …

Fusarium species manifests as an opportunistic infection with intrinsic resistance to most
antifungals. We present a case of a 63-year-old male with myelodysplasia who received …

We present a unique case of partial necrosis and cleft of the tongue caused by an endotracheal
tube, and highlight the importance of endotracheal tube positioning in patients requiring …

Hematopoietic stem cell transplantation (HSCT) has been used to treat many benign and
malignant diseases worldwide. Despite many advances in transplantation medicine and the …

The cystine/glutamate exchanger, System x c − , is comprised of two proteins, xCT and CD98
and is known to play a significant role in the protective response of cells to oxidative insult. …

Introduction Sickle cell disease (SCD), the most common autosomal recessive genetic
disorder worldwide, affects nearly every organ of the body and results in accelerated mortality. …

High-fat, high-sugar cafeteria diets and their association with obesity lead to increases in
metabolic syndrome and decreased lifespan in humans. As a growing health epidemic, the …

Normal development is governed by covalent modifications to chromatin that are mediated
by the reciprocal actions of Polycomb group (PcG) and Trithorax (TrxG) proteins, which …