A time-to-digital-converter-based CMOS smart temperature sensor

P Chen, CC Chen, CC Tsai… - IEEE Journal of Solid-State …, 2005 - ieeexplore.ieee.org
Chun-Chi Chen was born in Miaoli, Taiwan, ROC, in 1974. He received the MS degree
from National Taiwan University of Science and Technology, Taipei, Taiwan, ROC, in 2002, …

General features to enhance enzymatic activity of poly (ethylene terephthalate) hydrolysis

CC Chen, X Han, X Li, P Jiang, D Niu, L Ma, W Liu… - Nature Catalysis, 2021 - nature.com
Poly(ethylene terephthalate) (PET) is the most abundant polyester plastic and a major contributor
to plastic pollution. IsPETase, from the PET-assimilating bacterium Ideonella sakaiensis…

[HTML][HTML] Oxidative stress and nucleic acid oxidation in patients with chronic kidney disease

CC Sung, YC Hsu, CC Chen, YF Lin… - Oxidative medicine and …, 2013 - hindawi.com
Patients with chronic kidney disease (CKD) have high cardiovascular mortality and morbidity
and a high risk for developing malignancy. Excessive oxidative stress is thought to play a …

Structural studies reveal the molecular mechanism of PET ase

CC Chen, X Han, TP Ko, W Liu, RT Guo - The FEBS journal, 2018 - Wiley Online Library
Poly(ethylene terephthalate) ( PET ) is a class of plastic material widely used in modern society,
but large amounts of PET waste cause severe environmental problems. Obtained from a …

[HTML][HTML] Structural insight into catalytic mechanism of PET hydrolase

…, Y Zheng, TP Ko, L Xu, YS Cheng, CC Chen… - Nature …, 2017 - nature.com
PET hydrolase (PETase), which hydrolyzes polyethylene terephthalate (PET) into soluble
building blocks, provides an attractive avenue for the bioconversion of plastics. Here we …

Sub-60mV-swing negative-capacitance FinFET without hysteresis

KS Li, PG Chen, TY Lai, CH Lin… - 2015 IEEE …, 2015 - ieeexplore.ieee.org
In this work, we report the first Negative-Capacitance FinFET. ALD Hf042Zr058O2 is added
on top of the FinFET's gate stack. The test devices have a floating internal gate that can be …

[HTML][HTML] Structural insight into the electron transfer pathway of a self-sufficient P450 monooxygenase

…, X Li, Y Hu, J Min, X Yu, RT Guo, CC Chen - Nature …, 2020 - nature.com
Cytochrome P450 monooxygenases are versatile heme-thiolate enzymes that catalyze a wide
range of reactions. Self-sufficient cytochrome P450 enzymes contain the redox partners in …

[HTML][HTML] MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1

…, JC Lin, CC Chen, SH Pan, CT Wu, HY Chen… - Nature …, 2013 - nature.com
Dysregulation of microRNAs has a critical role in cancer progression. Here we identify an
intronic microRNA, miR-135b that is upregulated in highly invasive non-small-cell lung cancer …

[HTML][HTML] The role of Asprosin in patients with dilated cardiomyopathy

MS Wen, CY Wang, JK Yeh, CC Chen, ML Tsai… - BMC Cardiovascular …, 2020 - Springer
Background Asprosin is a novel fasting glucogenic adipokine discovered in 2016. Asprosin
induces rapid glucose releases from the liver. However, its molecular mechanisms and …

[HTML][HTML] Complete bio-degradation of poly (butylene adipate-co-terephthalate) via engineered cutinases

…, FC Tsai, L Dai, Q Zhang, Y Liu, CC Chen… - Nature …, 2023 - nature.com
Poly(butylene adipate-co-terephthalate) (PBAT), a polyester made of terephthalic acid (TPA),
1,4-butanediol, and adipic acid, is extensively utilized in plastic production and has …