User profiles for D. Janigro

Damir Janigro

Adjunct Professor of Physiology CWRU
Verified email at flocel.com
Cited by 19434

Engaging neuroscience to advance translational research in brain barrier biology

…, C Fahlke, G Fricker, C Iadecola, D Janigro… - Nature Reviews …, 2011 - nature.com
d | In early development the neuroependymal cells are connected to each other by strap
junctions (shown by arrows) that are believed to form the physical barrier restricting the …

[HTML][HTML] The role of brain barriers in fluid movement in the CNS: is there a 'glymphatic'system?

NJ Abbott, ME Pizzo, JE Preston, D Janigro… - Acta …, 2018 - Springer
Brain fluids are rigidly regulated to provide stable environments for neuronal function, eg, low
K + , Ca 2+ , and protein to optimise signalling and minimise neurotoxicity. At the same time…

The blood–brain barrier and epilepsy

E Oby, D Janigro - Epilepsia, 2006 - Wiley Online Library
During the past several years, there has been increasing interest in the role of the blood–brain
barrier (BBB) in epilepsy. Advances in neuroradiology have enhanced our ability to …

Serum S-100β as a possible marker of blood–brain barrier disruption

…, D Apollo, P Rasmussen, MR Mayberg, D Janigro - Brain research, 2002 - Elsevier
Two brain-specific proteins, S-100β and neuron-specific enolase (NSE), are released
systemically after cerebral lesions, but S-100β levels sometimes rise in the absence of neuronal …

Overexpression of multiple drug resistance genes in endothelial cells from patients with refractory epilepsy

…, W Bingaman, MR Mayberg, L Bengez, D Janigro - …, 2001 - Wiley Online Library
… Damir JanigroJanigro. Dr. Desai is supported by AHA-GIA. … D. Chyatte for providing
the aneurysm samples used for pilot studies on gene expression and Dr. B. …

Seizure‐promoting effect of blood–brain barrier disruption

…, K Hallene, T Diglaw, L Franic, I Najm, D Janigro - …, 2007 - Wiley Online Library
… (D) Seizure events are more common after BBB disruption in the anterior circulation and
seizures induced by intracarotid mannitol manifest usually contralaterally. The data show the …

Serum S100β: A noninvasive marker of blood‐brain barrier function and brain lesions

…, MA Vogelbaum, GH Barnett, D Janigro - … Journal of the …, 2003 - Wiley Online Library
… (D) There was a positive correlation between S100β levels and the size of vestibular
schwannoma (P < 0.01). Gd: gadolinium; Allmets: all metastatic brain tumors; Breast Met: breast …

[HTML][HTML] Consequences of repeated blood-brain barrier disruption in football players

…, E Blackman, D Stewart, J Ellis, R Butler, D Janigro - PloS one, 2013 - journals.plos.org
The acknowledgement of risks for traumatic brain injury in American football players has
prompted studies for sideline concussion diagnosis and testing for neurological deficits. While …

[HTML][HTML] The role of shear stress in Blood-Brain Barrier endothelial physiology

…, M Hossain, V Puvenna, N Marchi, D Janigro - BMC neuroscience, 2011 - Springer
… under flow was capable of discriminating the passage of substances accordingly to their
permeability order more efficiently that the BBB established under static condition (Panel D). …

Impaired K+ homeostasis and altered electrophysiological properties of post-traumatic hippocampal glia

…, DO Maris, MS Grady, HR Winn, D Janigro - Journal of …, 1999 - Soc Neuroscience
… Using a fluid percussion injury (FPI) model and patch-clamp recordings from hippocampal
slices, we have found impaired glial physiology 2 d after FPI. Electrophysiologically, we …