Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial

…, JL Mandzia, TJ Kleinig, D Turkel-Parrella… - The Lancet, 2020 - thelancet.com
Background Nerinetide, an eicosapeptide that interferes with post-synaptic density protein
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …

[HTML][HTML] The critical care management of spontaneous intracranial hemorrhage: a contemporary review

…, A Goffi, FG Zampieri, D Turkel-Parrella… - Critical Care, 2016 - Springer
Spontaneous intracerebral hemorrhage (ICH), defined as nontraumatic bleeding into the
brain parenchyma, is the second most common subtype of stroke, with 5.3 million cases and …

The VASOGRADE: a simple grading scale for prediction of delayed cerebral ischemia after subarachnoid hemorrhage

…, W Qian, E Kouzmina, TR Marotta, D Turkel-Parrella… - Stroke, 2015 - Am Heart Assoc
Background and Purpose— Patients are classically at risk of delayed cerebral ischemia (DCI)
after aneurysmal subarachnoid hemorrhage. We validated a grading scale—the …

[HTML][HTML] Aneurysmal subarachnoid haemorrhage from a neuroimaging perspective

…, A Mansur, A Murphy, D Turkel-Parrella… - Critical Care, 2014 - Springer
Neuroimaging is a key element in the management of patients suffering from subarachnoid
haemorrhage (SAH). In this article, we review the current literature to provide a summary of …

Characteristics of a COVID-19 cohort with large vessel occlusion: a multicenter international study

…, M Goyal, H Wu, J Cohen, D Turkel-Parrella… - …, 2022 - journals.lww.com
BACKGROUND: The mechanisms and outcomes in coronavirus disease (COVID-19)–associated
stroke are unique from those of non–COVID-19 stroke. OBJECTIVE: To describe the …

[HTML][HTML] Recurrence and coniglobus volumetric resolution of subacute and chronic subdural hematoma post-middle meningeal artery embolization

…, P Ye, DS Gordon, KM Arcot, D Turkel-Parrella… - Diagnostics, 2021 - mdpi.com
Objective: To study the efficacy of middle meningeal artery (MMA) embolization for the treatment
of chronic subdural hematoma (SDH) and characterize its post-embolization volumetric …

[PDF][PDF] Managing aneurysmal subarachnoid hemorrhage: it takes a team

…, O MANOEL, D TURKEL-PARRELLA… - … Clinic Journal of …, 2015 - academia.edu
Patients with aneurysmal subarachnoid hemorrhage are at high risk of complications,
including rebleeding, delayed cerebral ischemia, cerebral infarction, and death. This review …

Stroke treatment delay limits outcome after mechanical thrombectomy: stratification by arrival time and ASPECTS

…, J Farkas, J Liff, D TurkelParrella… - Journal of …, 2020 - Wiley Online Library
BACKGROUND AND PURPOSE Mechanical thrombectomy (MT) has helped many patients
achieve functional independence. The effect of time‐to‐treatment based in specific epochs …

Validation of carotid artery revascularization coding in Ontario health administrative databases

…, G Saposnik, JV Tu, D Turkel-Parrella… - Clinical and …, 2016 - utpjournals.press
Purpose The positive predictive value (PPV) of carotid endarterectomy (CEA) and carotid
artery stenting (CAS) procedure and post-operative complication coding were assessed in …

Safety of early pharmacological thromboprophylaxis after subarachnoid hemorrhage

AL de Oliveira Manoel, D Turkel-Parrella… - Canadian Journal of …, 2014 - cambridge.org
ObjectiveThe recent guidelines on management of aneurysmal subarachnoid hemorrhage (aSAH)
advise pharmacological thromboprophylaxis (PTP) after aneurysm obliteration. …