Proinflammatory cytokines in the prefrontal cortex of teenage suicide victims

…, HS Rizavi, X Ren, J Fareed, DA Hoppensteadt… - Journal of psychiatric …, 2012 - Elsevier
Teenage suicide is a major public health concern, but its neurobiology is not well understood.
Proinflammatory cytokines play an important role in stress and in the pathophysiology of …

Treatment of severe veno-occlusive disease with defibrotide: compassionate use results in response without significant toxicity in a high-risk population

…, C Wheeler, R Nath, D Hoppensteadt… - Blood, The Journal …, 1998 - ashpublications.org
Hepatic veno-occlusive disease (VOD) is the most common of the regimen-related toxicities
accompanying stem cell transplantation (SCT). Despite aggressive therapies, including the …

Disseminated intravascular coagulation: an update on pathogenesis, diagnosis, and therapeutic strategies

…, J Fareed, I Elalamy, D Hoppensteadt… - Clinical and applied …, 2018 - journals.sagepub.com
Disseminated intravascular coagulation (DIC) is an acquired clinicobiological syndrome
characterized by widespread activation of coagulation leading to fibrin deposition in the …

An update on heparins at the beginning of the new millennium

DA Hoppensteadt, RL Bick… - Seminars in thrombosis …, 2000 - thieme-connect.com
Unfractionated heparin has enjoyed the sole anticoagulant status for almost half a century.
Besides an effective anticoagulant, this drug has been used in several additional indications. …

Pharmacodynamic and pharmacokinetic properties of enoxaparin: implications for clinical practice

J Fareed, D Hoppensteadt, J Walenga, O Iqbal… - Clinical …, 2003 - Springer
Enoxaparin is a low-molecular-weight heparin (LMWH) that differs substantially from unfractionated
heparin (UFH) in its pharmacodynamic and pharmacokinetic properties. Some of the …

Pro-inflammatory biomakers in depression: treatment with venlafaxine

…, A Halaris, O Iqbal, D Hoppensteadt… - The World Journal of …, 2009 - Taylor & Francis
High levels of pro-inflammatory biomarkers have been reported in depression. In the present
study, five pro-inflammatory biomarkers were measured in the blood of patients with major …

Recurrent miscarriage syndrome and infertility due to blood coagulation protein/platelet defects: a review and update

RL Bick, D Hoppensteadt - Clinical and applied thrombosis …, 2005 - journals.sagepub.com
Three-hundred fifty-one women were referred for thrombosis and hemostasis evaluation
after suffering recurrent miscarriages. All patients were referred by a high-risk obstetrician or …

Multi-institutional use of defibrotide in 88 patients after stem cell transplantation with severe veno-occlusive disease and multisystem organ failure: response without …

…, D Warren, P Momtaz, D Hoppensteadt… - Blood, The Journal …, 2002 - ashpublications.org
Veno-occlusive disease (VOD) is the most common regimen-related toxicity accompanying
stem cell transplantation (SCT). Severe VOD complicated by multisystem organ failure (MOF) …

Oligosaccharide mapping of low-molecular-weight heparins: structure and activity differences

…, HM Wang, JM Walenga, D Hoppensteadt… - Journal of medicinal …, 1990 - ACS Publications
Low molecular weight heparins from a variety of commercial sources were examined.
These had been prepared by several methods including peroxidative cleavage, nitrous acid …

Synthetic oligosaccharides can replace animal-sourced low–molecular weight heparins

…, V Pagadala, W Dou, DM Hoppensteadt… - Science translational …, 2017 - science.org
Low–molecular weight heparin (LMWH) is used clinically to treat clotting disorders. As an
animal-sourced product, LMWH is a highly heterogeneous mixture, and its anticoagulant …