In 1990, an international grading system for cardiac allograft biopsies was adopted by the
International Society for Heart Transplantation. This system has served the heart transplant …

Sustained cardiac pressure overload induces hypertrophy and pathological remodeling,
frequently leading to heart failure. Genetically engineered hyperstimulation of guanosine 3′,5…

Subcellular localization of nitric oxide (NO) synthases with effector molecules is an important
regulatory mechanism for NO signalling 1 . In the heart, NO inhibits L-type Ca 2+ channels …

The Association for European Cardiovascular Pathology and the Society for Cardiovascular
Pathology have produced this position paper concerning the current role of endomyocardial …

Post-translational modification and functional impairment of proteins through carbamylation
is thought to promote vascular dysfunction during end-stage renal disease. Cyanate, a …

Neuropilin-1 (Npn-1) is a receptor that binds multiple ligands from structurally distinct
families, including secreted semaphorins (Sema) and vascular endothelial growth factors (VEGF). …

Background— Preconditioning phenomena provide evidence for adaptive responses to
ischemia that have important implications for treatment/prevention of myocardial infarction. …

Conclusions In the modern era, multimodality imaging is essential in the diagnosis and
management of pericardial syndromes. Echocardiography is the initial test for most pericardial …

Objectives : We evaluated the role of myocardial delayed-enhancement (MDE) magnetic
resonance imaging (MRI) for noninvasive detection of fibrosis in Arrhythmogenic right …

Cardiac pressure load stimulates hypertrophy, often leading to chamber dilation and dysfunction.
ROS contribute to this process. Here we show that uncoupling of nitric oxide synthase–…