Mitral valve prolapse is a common valvular abnormality that is the most common cause of
severe non-ischaemic mitral regurgitation in the USA. The overall prognosis of patients with …

To the Editor: A previously healthy 78-year-old woman presented with facial flushing,
palpitations, diarrhea, and generalized weakness. The serum serotonin level was markedly …

Background Antithrombotic prophylaxis with oral anticoagulation (OAC) substantially reduces
stroke and mortality in patients with atrial fibrillation (AF). Hypothesis Analysis of data in …

Background. Native valve endocarditis is frequently managed with antibiotics alone, but
prosthetic valve endocarditis usually requires an early operation. What is the best treatment of …

Background: Nitric oxide is a messenger molecule of the nervous system, which is produced
by the enzyme nitric oxide synthase, which may regulate cyclic guanosine monophosphate …

We report an unusual presentation of cardiac paraganglioma with acute myocardial
infarction and stroke induced by exercise and review the literature regarding this rare …

Much of the conventional wisdom about the prevalance, causes, diagnosis, symptoms, effects,
and treament of mitral valve prolapse (MVP) is changing. MVP has a benign course and …

Background: Oral anticoagulation (OAC) with a vitamin K antagonist (VKA) or non-VKA OAC
(NOAC) reduces stroke risk in patients with atrial fibrillation (AF). We aimed to identify …

… The new material that the Hayek family and Bartley and Kresge provided to us and the
interviews we undertook gave us the ability to tell Hayek’s story in a way that had never been …

Drug therapy plays a key role in the management of valvular heart disease, though in many
cases it does not alter its course or delay the need for surgery. The importance of drug …