[HTML][HTML] Detection of Bacterial 16S rRNA and Identification of Four Clinically Important Bacteria by Real-Time PCR

…, YI Kwak, PE Waterman, EP Lesho, P Mc Gann - PloS one, 2012 - journals.plos.org
Within the paradigm of clinical infectious disease research, Acinetobacter baumannii,
Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa represent the four most …

AB5075, a highly virulent isolate of Acinetobacter baumannii, as a model strain for the evaluation of pathogenesis and antimicrobial treatments

…, CL Honnold, MC Wise, PE Waterman, EP Lesho… - MBio, 2014 - Am Soc Microbiol
Acinetobacter baumannii is recognized as an emerging bacterial pathogen because of traits
such as prolonged survival in a desiccated state, effective nosocomial transmission, and an …

[HTML][HTML] A novel method of consensus pan-chromosome assembly and large-scale comparative analysis reveal the highly flexible pan-genome of Acinetobacter …

…, XZ Huang, E Beck, DM Harkins, M Kim, EP Lesho… - Genome biology, 2015 - Springer
Background Infections by pan-drug resistant Acinetobacter baumannii plague military and
civilian healthcare systems. Previous A. baumannii pan-genomic studies used modest sample …

Clinical use of colistin induces cross-resistance to host antimicrobials in Acinetobacter baumannii

…, SM Cagle, SM Ray, P McGann, J Pohl, EP Lesho… - MBio, 2013 - Am Soc Microbiol
The alarming rise in antibiotic resistance has led to an increase in patient mortality and
health care costs. This problem is compounded by the absence of new antibiotics close to …

Complete Sequence of a Novel 178-Kilobase Plasmid Carrying blaNDM-1 in a Providencia stuartii Strain Isolated in Afghanistan

…, YI Kwak, RA Kuschner, EP Lesho… - Antimicrobial Agents …, 2012 - Am Soc Microbiol
In response to global concerns over the spread of the New Delhi metallo-β-lactamase gene
1, bla NDM-1 , a monthly surveillance program was initiated in September 2010. All …

Analysis of Serial Isolates of mcr-1-Positive Escherichia coli Reveals a Highly Active ISApl1 Transposon

…, EP Lesho, M Hinkle, P McGann - Antimicrobial agents …, 2017 - Am Soc Microbiol
The emergence of a transferable colistin resistance gene (mcr-1) is of global concern. The
insertion sequence ISApl1 is a key component in the mobilization of this gene, but its role …

The slow-motion catastrophe of antimicrobial resistance and practical interventions for all prescribers

EP Lesho, M Laguio-Vila - Mayo Clinic Proceedings, 2019 - Elsevier
All medical and surgical specialties depend on the pool of effective antibiotics that continues
to evaporate because of the increasing prevalence of drug-resistant bacteria. Antimicrobial-…

A diverse panel of clinical Acinetobacter baumannii for research and development

…, EP Lesho, JW Bennett, P Mc Gann - Antimicrobial agents …, 2020 - Am Soc Microbiol
Over the past two decades, Acinetobacter baumannii has emerged as a leading cause of
nosocomial infections worldwide. Of particular concern are panresistant strains, leading the …

[HTML][HTML] An overview of osteopathic medicine

EP Lesho - Archives of family medicine, 1999 - triggered.stanford.clockss.org
Despite an initial lack of acceptance by mainstream medicine, and amidst projections of a
serious oversupply of physicians, the osteopathic profession continues to grow, successfully …

[HTML][HTML] Characteristics of Plasmids in Multi-Drug-Resistant Enterobacteriaceae Isolated during Prospective Surveillance of a Newly Opened Hospital in Iraq

…, LSM Glenn, JA Ake, W Su, MP Nikolich, EP Lesho - PloS one, 2012 - journals.plos.org
Background Gram-negative multidrug-resistant (MDR) bacteria are major causes of nosocomial
infections, and antibiotic resistance in these organisms is often plasmid mediated. Data …