Background: α-Hydroxy acids (AHAs) have been reported to improve aging skin. The mechanisms
of action of AHAs on epidermal and dermal compartments need clarification. Objective…

Hyperkeratinization is a primary or fundamental event in a majority of today's skin disorders.
Hyperkeratinization is usually the result of decreased desquamation due to increased …

A double-blind study comparing the response of 21 patients with psoriatic arthritis to a series
of three parenteral injections of methotrexate at 10-day intervals with the response to a …

Complete responses lasting from 4 to 14 years were documented in 65 of 331 (20%) patients
with cutaneous T cell lymphoma treated with topical mechlorethamine (HN2) between …

Topical preparations containing α-hydroxy acids and closely related compounds were
found to exert profound effects on epidermal keratinization in ichthyosis. Therapeutically …

The hydroxyacids are represented by the α-hydroxyacids, β-hydroxyacids, polyhydroxy acids,
and bionic acids. Together, these ingredients form a class of compounds with unparalleled …

RESULTS Differential counting of types o1 hair roots. Roots of hairs pulled from the human
scalp may be identified as either anagen (growing) or telogen (resting) when viewed …

The carboxylic acids include alpha‐hydroxyacids (AHAs), polyhydroxy acids (PHAs), aldobionic
acids (ABAs), retinoic acid, vitamin C and azelaic acid. They all have therapeutic actions…

On the basis of clinical, histological, and cellular kinetic observations, a separation of the
major ichthyosiform dermatoses into four groups is proposed. Ichthyosis vulgaris patients have …

… Van Scott whether he has any data as to how long the depression of the white … Van Scott
has any information on this point. … Van Scott treated any patients with psoriatic arthritis with the …