A calcium antagonist vs a non–calcium antagonist hypertension treatment strategy for patients with coronary artery disease: the International Verapamil-Trandolapril …

…, RM Cooper-DeHoff, RG Marks, P Kowey, FH Messerli… - Jama, 2003 - jamanetwork.com
ContextDespite evidence of efficacy of antihypertensive agents in treating hypertensive
patients, safety and efficacy of antihypertensive agents for coronary artery disease (CAD) have …

Fixed-dose combinations improve medication compliance: a meta-analysis

…, G Kamalakkannan, S Parkar, FH Messerli - The American journal of …, 2007 - Elsevier
BACKGROUND: Compliance with treatment is a sine qua non for successful treatment of
chronic conditions like hypertension. Fixed-dose combinations are designed to simplify the …

[HTML][HTML] Feasibility of treating prehypertension with an angiotensin-receptor blocker

…, HR Black, RH Grimm Jr, FH Messerli… - … England Journal of …, 2006 - Mass Medical Soc
Background Prehypertension is considered a precursor of stage 1 hypertension and a
predictor of excessive cardiovascular risk. We investigated whether pharmacologic treatment of …

Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension: a randomized controlled trial

…, V Fonseca, RE Katholi, JB McGill, FH Messerli… - Jama, 2004 - jamanetwork.com
Contextβ-Blockers have been shown to decrease cardiovascular risk in patients with
hypertension and type 2 diabetes mellitus (DM); however, some components of the metabolic …

A meta-analysis of the effects of treatment on left ventricular mass in essential hypertension

…, M Schneider, P Martus, FH Messerli… - The American journal of …, 2003 - Elsevier
PURPOSE: Antihypertensive medications have different effects on left ventricular mass. We
conducted a meta-analysis of double-blind trials that measured the effects of …

Dogma disputed: can aggressively lowering blood pressure in hypertensive patients with coronary artery disease be dangerous?

FH Messerli, G Mancia, CR Conti… - Annals of internal …, 2006 - acpjournals.org
Messerli and coauthors had full access to the data, and this manuscript represents their …
Messerli and colleagues suggest that there is a nadir for diastolic blood pressure below which …

Essential hypertension

FH Messerli, B Williams, E Ritz - The Lancet, 2007 - thelancet.com
Essential hypertension can be defined as a rise in blood pressure of unknown cause that
increases risk for cerebral, cardiac, and renal events. In industrialised countries, the risk of …

Are β-blockers efficacious as first-line therapy for hypertension in the elderly?: a systematic review

FH Messerli, E Grossman, U Goldbourt - Jama, 1998 - jamanetwork.com
Objective.—To assess antihypertensive efficacy of β-blockers and their effects on cardiovascular
morbidity and mortality and all-cause morbidity compared with diuretics in elderly …

Should a moratorium be placed on sublingual nifedipine capsules given for hypertensive emergencies and pseudoemergencies?

E Grossman, FH Messerli, T Grodzicki, P Kowey - Jama, 1996 - jamanetwork.com
Over the past 2 decades, nifedipine in the form of capsules has become widely popular in the
treatment of hypertensive emergencies. Unlike other agents, such as sodium nitroprusside, …

Obesity paradox in patients with hypertension and coronary artery disease

S Uretsky, FH Messerli, S Bangalore… - The American journal of …, 2007 - Elsevier
PURPOSE: An obesity paradox, a “paradoxical” decrease in morbidity and mortality with
increasing body mass index (BMI), has been shown in patients with heart failure and those …