It remains unclear how and why autoimmunity occurs. Here we show evidence for a previously
unrecognized and possibly general mechanism of autoimmunity. This new finding was …

Studies aiming to identify susceptibility genes for schizophrenia and other complex psychiatric
disorders are faced with the confounds of subjective clinical criteria, commonly occurring …

Effectively evaluating visualization techniques is a difficult task often assessed through feedback
from user studies and expert evaluations. This work presents an alternative approach to …

Anti-neutrophil cytoplasmic antibody–associated (ANCA-associated) small vessel necrotizing
vasculitis is caused by immune-mediated inflammation of the vessel wall and is diagnosed …

… The preneoplastic hamster cell lines, sup I cells and sup II, used in this work have also been
described by Preston et al. (52). RKO human colorectal carcinoma cells were obtained from …

Antineutrophil cytoplasmic autoantibody (ANCA) causes vascular injury that leads to small-vessel
vasculitis. Patients with ANCA aberrantly express neutrophil granule–encoding genes, …

Caffeic acid phenethyl ester (CAPE), which is derived from the propolis of bee hives, was
shown previously to block tumor promoter- and carcinogen-generated oxidative processes in …

Lysosomal membrane protein 2 (LAMP-2) is a target of antineutrophil cytoplasmic
autoantibodies (ANCA) in addition to the more commonly known targets proteinase 3 and …

Objective The development of pathogenic antineutrophil cytoplasmic antibodies (ANCAs)
can result in systemic small vessel vasculitis. However, the breakdown in immune tolerance …

… 1980, in Atlanta, Georgia. Requests for reprints should be addressed to Dr. Gary A…
Preston. * Present address: US Public Health Service Hospital, 1131 14th S, Seattle, WA 98114. …