Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

…, K Chen, JC Wang, N Chatterjee, W Hu, MP Wong… - Nature …, 2012 - nature.com
To identify common genetic variants that contribute to lung cancer susceptibility, we conducted
a multistage genome-wide association study of lung cancer in Asian women who never …

[HTML][HTML] Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

…, Q Cai, YC Hong, HN Kim, YL Wu, MP Wong… - Nature …, 2023 - nature.com
Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain
only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage …

[PDF][PDF] Characterization of large structural genetic mosaicism in human autosomes

…, DV Berg, JC Wang, N Wentzensen, MP Wong… - The American Journal of …, 2015 - cell.com
Analyses of genome-wide association study (GWAS) data have revealed that detectable
genetic mosaicism involving large (>2 Mb) structural autosomal alterations occurs in a fraction …

G enetic variants associated with longer telomere length are associated with increased lung cancer risk among never‐smoking women in Asia: a report from the …

…, YH Chen, HC Lin, T Wu, MP Wong… - … journal of cancer, 2015 - Wiley Online Library
Recent evidence from several relatively small nested case‐control studies in prospective
cohorts shows an association between longer telomere length measured phenotypically in …

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings …

…, M Song, HN Kim, MP Wong, YC Hong… - Human molecular …, 2017 - academic.oup.com
To evaluate associations by EGFR mutation status for lung adenocarcinoma risk among
never-smoking Asian women, we conducted a meta-analysis of 11 loci previously identified in …

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

…, Y Chen, WY Lim, J Liu, MP Wong… - Human molecular …, 2016 - academic.oup.com
Genome-wide association studies (GWAS) of lung cancer in Asian never-smoking women
have previously identified six susceptibility loci associated with lung cancer risk. To further …

[HTML][HTML] Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never …

…, K Shiraishi, K Yu, K Matsuo, MP Wong, YC Hong… - Genomics, 2020 - Elsevier
We investigated whether genetic susceptibility to tuberculosis (TB) influences lung
adenocarcinoma development among never-smokers using TB genome-wide association study (…

Interactions between household air pollution and GWAS-identified lung cancer susceptibility markers in the Female Lung Cancer Consortium in Asia (FLCCA)

…, MH Shin, YC Hong, K Matsuo, K Chen, MP Wong… - Human genetics, 2015 - Springer
We previously carried out a multi-stage genome-wide association study (GWAS) on lung
cancer among never smokers in the Female Lung Cancer Consortium in Asia (FLCCA) (6,609 …

[HTML][HTML] Sub-multiplicative interaction between polygenic risk score and household coal use in relation to lung adenocarcinoma among never-smoking women in Asia

…, YC Hong, K Matsuo, K Chen, MP Wong… - Environment …, 2021 - Elsevier
We previously identified 10 lung adenocarcinoma susceptibility loci in a genome-wide
association study (GWAS) conducted in the Female Lung Cancer Consortium in Asia (FLCCA), …

Underlying Causes of TIA and Minor Ischemic Stroke and Risk of Major Vascular Events

…, Y Wang, F Chandgfend, G Contago, J Hongyun… - JAMA …, 2023 - jamanetwork.com
… Professor Wong reported receiving honoraria as a member of a steering committee for
Johnson & Johnson, AstraZeneca, and Bayer AG and honoraria for participation in clinical trials, …