Significance: Although most researches into the changes in skin with age focus on the
unwelcome aesthetic aspects of the aging skin, skin deterioration with age is more than a merely …

The pig has been a well-recognized experimental animal in biomedical research for many
centuries. Physiological and anatomical similarities between man and pig made this animal a …

Background/purpose: The aging process has been studied with fervor recently, given our
shifting demographics. Since age's effects are so manifest in skin's appearance, structure, …

Written by experienced and internationally renowned contributors, this is the fourth edition of
what has become the standard reference for cosmetic scientists and dermatologists seeking …

A comparative study was undertaken in rats, rabbits, miniature swine and man, in which the
percutaneous absorption of the following compounds, labeled with 14 C or 35 S, were …

We studied the percutaneous penetration of 21 organic chemicals. The experimental m thod
consi ted of the application of the chemical to the human forearm and quantitating it …

Pesticides labeled with radioactive carbon ( 14 C) (parathion, malathion, and carbaryl) were
applied on the skin of volunteers. The experimental variable studied was the effect of …

Twelve radiolabeled 14 C-pesticides and herbicides were applied to the forearms of human
subjects, and the urinary excretion of 14 C was quantitated. Data obtained after iv dosing …

During 64 months (1977 to 1983), twelve dermatologists from various sections of the United
States studied a total of 713 patients with cosmetic dermatitis out of an estimated total of …

Since publication of the Second Edition in 1989, numerous innovations have occurred that
affect the way scientists look at issues in the field of percutaneous absorption. Focusing on …