… The current iteration of this article differs from that of Douketis et al 6 in the Antithrombotic
and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical …

Obesity is now reaching epidemic proportions in both developed and developing countries
and is affecting not only adults but also children and adolescents. Over the last 20 years, …

Background It is uncertain whether bridging anticoagulation is necessary for patients with
atrial fibrillation who need an interruption in warfarin treatment for an elective operation or …

Background Warfarin is a highly efficacious oral anticoagulant, but its use is limited by a well-founded
fear of bleeding. Drug and food interactions are frequently cited as causes of …

… D. Giannis—no relevant conflicts for present work. JD Douketis—no relevant conflicts for
present … Douketis contributed to the concept, analysis/interpretation of data, critical writing, and …

This article discusses the perioperative management of antithrombotic therapy and is part of
the American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th …

Background: Clinicians should consider the clinical impact of anticoagulant-related
bleeding when deciding on the duration of anticoagulant therapy in patients with venous …

Context.—The most serious complication of deep vein thrombosis (DVT) or nonfatal pulmonary
embolism (PE) is fatal PE. However, reliable estimates as to the risk of fatal PE in patients …

Background The optimum duration of prophylaxis against venous-thromboembolism after
total hip or knee replacement is uncertain. Our primary objective was to establish the efficacy …

Background: Underutilization of anticoagulant prophylaxis may be due to lack of evidence
that prophylaxis prevents clinically important outcomes in hospitalized medical patients at risk …