Combination therapy in hypertension

AH Gradman, JN Basile, BL Carter, GL Bakris… - Journal of the American …, 2010 - Elsevier
The goal of antihypertensive therapy is to abolish the risks associated with blood pressure (BP)
elevation without adversely affecting quality of life. Drug selection is based on efficacy in …

Self-measured blood pressure monitoring at home: a joint policy statement from the American Heart Association and American Medical Association

D Shimbo, NT Artinian, JN Basile, LR Krakoff… - Circulation, 2020 - Am Heart Assoc
The diagnosis and management of hypertension, a common cardiovascular risk factor among
the general population, have been based primarily on the measurement of blood pressure …

Combination therapy in hypertension

AH Gradman, JN Basile, BL Carter… - The Journal of …, 2011 - Wiley Online Library
Editor’s Note: The American Society of Hypertension is publishing a series of Position Papers
in their official journals throughout the 2008–2011 years. The following Position Paper …

Clinical events in high-risk hypertensive patients randomly assigned to calcium channel blocker versus angiotensin-converting enzyme inhibitor in the …

…, LM Simpson, MH Alderman, SA Atlas, JN Basile… - …, 2006 - Am Heart Assoc
The Antihypertensive and Lipid-Lowering treatment to prevent Heart Attack Trial (ALLHAT)
provides a unique opportunity to compare the long-term relative safety and efficacy of …

Orthostatic hypotension in the ACCORD (Action to Control Cardiovascular Risk in Diabetes) blood pressure trial: prevalence, incidence, and prognostic significance

…, GW Evans, KL Margolis, J Barzilay, JN Basile… - …, 2016 - Am Heart Assoc
Orthostatic hypotension (OH) is associated with hypertension and diabetes mellitus. However,
in populations with both hypertension and diabetes mellitus, its prevalence, the effect of …

Plasma renin test–guided drug treatment algorithm for correcting patients with treated but uncontrolled hypertension: a randomized controlled trial

BM Egan, JN Basile, SU Rehman… - American journal of …, 2009 - academic.oup.com
Background Undefined pathophysiologic mechanisms likely contribute to unsuccessful
antihypertensive drug therapy. The renin test–guided therapeutic (RTGT) algorithm is based on …

Rationale and design for the blood pressure intervention of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial

…, MH Alderman, K Peterson, A Bertoni, JN Basile… - The American journal of …, 2007 - Elsevier
The Action to Control Cardiovascular Disease in Diabetes (ACCORD) blood pressure trial is
an unmasked, open-label, randomized trial with a sample size of 4,733 participants. This …

Clinical outcomes by race in hypertensive patients with and without the metabolic syndrome: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack …

…, C Baimbridge, CJ Bareis, JN Basile… - Archives of Internal …, 2008 - jamanetwork.com
Background Antihypertensive drugs with favorable metabolic effects are advocated for first-line
therapy in hypertensive patients with metabolic/cardiometabolic syndrome (MetS). We …

Blood pressure control by drug group in the Antihypertensive and Lipid‐Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

…, RA Preston, BR Davis, JN Basile… - The Journal of …, 2008 - Wiley Online Library
Blood pressure (BP) control rates and number of antihypertensive medications were compared
(average follow‐up, 4.9 years) by randomized groups: chlorthalidone, 12.5–25 mg/d (n=…

Cardiovascular outcomes using doxazosin vs. chlorthalidone for the treatment of hypertension in older adults with and without glucose disorders: a report from the …

…, T Wiegmann, JO Ciocon, JN Basile - The Journal of …, 2004 - Wiley Online Library
Insulin resistance underlies most glucose disorders in adults and is associated with an
increased risk of cardiovascular disease. Alpha blockers decrease insulin resistance, whereas …