PURPOSE: The purpose of this study was to analyze results of adjuvant stereotactic radiosurgery
(SRS) targeted at resection cavities of brain metastases without whole-brain irradiation …

Despite decades of clinical trials investigating new treatment modalities for glioblastoma
multiforme (GBM), there have been no significant treatment advances since the 1980s. …

ABX-CBL, an immunoglobulin M murine monoclonal antibody, recognizes CD147 and
initiates cell killing through complement-mediated lysis. In a dose-finding trial, 27 patients with …

Forty-seven patients with hematologic neoplasia received recombinant human granulocyte-macrophage
colony-stimulating factor (rhGM-CSF) by daily 2-hour infusion following …

Osteoarthritis (OA) is the most commonly diagnosed form of arthritis, and it contributes
significantly to the functional incapacities of the aging population. The primary manifestation is …

To determine whether reduced nerve growth factor (NGF) and/or its high affinity receptor, trkA,
play a role in the pathophysiology of Rett syndrome (RS), we used immunohistochemistry …

Current therapeutic goals for treatment of Glioblastoma Multiforme (GBM) involve gross total
resection followed by multifractionated focal external beam radiation therapy (EBRT). …

OBJECTIVE: Cluster headache (CH) is a severe unilateral and periorbital facial pain syndrome
that is often associated with autonomic symptoms, including ipsilateral lacrimation, nasal …

This paper describes the background and current status of an OMERACT facilitated effort to
improve the consistency of adverse event reporting in rheumatology clinical trials. The …

This six-month, double-blind, controlled, randomized, parallel study at 13 medical centers
compared the safety and efficacy of nabumetone (1,000 mg taken at bedtime) with that of …