Purpose A subset of patients treated for Lyme disease report persistent or recurrent symptoms
of unknown etiology named post-treatment Lyme disease syndrome (PTLDS). This study …

It has long been observed in clinical practice that a subset of patients with Lyme disease
report a constellation of symptoms such as fatigue, cognitive difficulties, and musculoskeletal …

Background: The increased incidence and geographic expansion of Lyme disease has made
it the most common vector-borne infection in North America. Post-treatment Lyme disease …

In general, the prognosis after treatment of uncomplicated infection with Borrelia burgdorferi,
the causative agent of Lyme disease, is favorable. However, the clinical management of …

Saccharomyces cerevisiae (brewer's or baker's yeast) is a common colonizer of human
mucosal surfaces, but its role as a clinically important pathogen has been unclear. We report …

OBJECTIVES: The study objective is to demonstrate the clinical and research utility of an
operationalized definition of post-treatment Lyme disease syndrome (PTLDS), as proposed by …

Lyme disease is usually diagnosed and treated based on clinical manifestations. However,
laboratory testing is useful for patients with confusing presentations and for validation of …

Lyme disease is a tick-borne illness caused by the bacterium Borrelia burgdorferi , and
approximately 10 to 20% of patients report persistent symptoms lasting months to years despite …

Approximately 10% to 20% of patients optimally treated for early Lyme disease develop
persistent symptoms of unknown pathophysiology termed posttreatment Lyme disease …

Direct molecular tests in blood for early Lyme disease can be insensitive due to low amount
of circulating Borrelia burgdorferi DNA. To address this challenge, we have developed a …