MYH9 is associated with nondiabetic end-stage renal disease in African Americans
…, SB Nicholas, MV Pahl, JR Schelling, JR Sedor… - Nature …, 2008 - nature.com
As end-stage renal disease (ESRD) has a four times higher incidence in African Americans
compared to European Americans, we hypothesized that susceptibility alleles for ESRD …
compared to European Americans, we hypothesized that susceptibility alleles for ESRD …
Chronic kidney disease and its complications
R Thomas, A Kanso, JR Sedor - Primary care: Clinics in office practice, 2008 - Elsevier
Chronic kidney disease (CKD) is a complex disease affecting more than 20 million
individuals in the United States. Progression of CKD is associated with a number of serious …
individuals in the United States. Progression of CKD is associated with a number of serious …
[PDF][PDF] EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt
…, H Guo, A Petty, J Cutter, JP Basilion, J Sedor… - Cancer cell, 2009 - cell.com
Both pro- and antioncogenic properties have been attributed to EphA2 kinase. We report
that a possible cause for this apparent paradox is diametrically opposite roles of EphA2 in …
that a possible cause for this apparent paradox is diametrically opposite roles of EphA2 in …
[HTML][HTML] Rituximab or cyclosporine in the treatment of membranous nephropathy
…, PE Gipson, DV Rizk, JR Sedor… - … England Journal of …, 2019 - Mass Medical Soc
Background B-cell anomalies play a role in the pathogenesis of membranous nephropathy.
B-cell depletion with rituximab may therefore be noninferior to treatment with cyclosporine for …
B-cell depletion with rituximab may therefore be noninferior to treatment with cyclosporine for …
[HTML][HTML] An atlas of healthy and injured cell states and niches in the human kidney
Understanding kidney disease relies on defining the complexity of cell types and states, their
associated molecular profiles and interactions within tissue neighbourhoods 1 . Here we …
associated molecular profiles and interactions within tissue neighbourhoods 1 . Here we …
Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway
…, T Alexandrou, JR Schelling, JS Rhim, JR Sedor… - Nature cell …, 2001 - nature.com
Interactions between Eph receptor tyrosine kinases (RTKs) and membrane-anchored ephrin
ligands critically regulate axon pathfinding and development of the cardiovascular system, …
ligands critically regulate axon pathfinding and development of the cardiovascular system, …
[HTML][HTML] Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach
The Nephrotic Syndrome Study Network (NEPTUNE) is a North American multicenter
collaborative consortium established to develop a translational research infrastructure for …
collaborative consortium established to develop a translational research infrastructure for …
Proteinuria as a surrogate outcome in CKD: report of a scientific workshop sponsored by the National Kidney Foundation and the US Food and Drug Administration
…, D Cattran, A Friedman, WG Miller, J Sedor… - American Journal of …, 2009 - Elsevier
Changes in proteinuria have been suggested as a surrogate outcome for kidney disease
progression to facilitate the conduct of clinical trials. This report summarizes a workshop …
progression to facilitate the conduct of clinical trials. This report summarizes a workshop …
Hospital-acquired urinary tract infections associated with the indwelling catheter
J Sedor, SG Mulholland - Urologic Clinics of North America, 1999 - Elsevier
The indwelling urethral urinary catheter is used in as many as 25% of patients admitted to
hospitals in the United States. These catheters are commonly placed in association with …
hospitals in the United States. These catheters are commonly placed in association with …
APOL1 localization in normal kidney and nondiabetic kidney disease
…, S Ganesan, LA Bruggeman, JR Sedor - Journal of the …, 2011 - journals.lww.com
In patients of African ancestry, genetic variants in APOL1, which encodes apolipoprotein L1,
associate with the nondiabetic kidney diseases, focal segmental glomerulosclerosis (FSGS)…
associate with the nondiabetic kidney diseases, focal segmental glomerulosclerosis (FSGS)…