Early and long-term clinical outcomes associated with reinfarction following fibrinolytic administration in the Thrombolysis in Myocardial Infarction trials

CM Gibson, J Karha, SA Murphy, D James… - Journal of the American …, 2003 - jacc.org
Objectives : We hypothesized that early recurrent myocardial infarction (MI) following
fibrinolytic administration would be assessed with higher mortality at both 30 days and 2 years. …

[HTML][HTML] Cerebral embolic protection during transcatheter aortic-valve replacement

…, S Horr, L Sondergaard, J Karha… - … England Journal of …, 2022 - Mass Medical Soc
Background Transcatheter aortic-valve replacement (TAVR) for the treatment of aortic
stenosis can lead to embolization of debris. Capture of debris by devices that provide cerebral …

In unstable angina or non–ST-segment acute coronary syndrome, should patients with multivessel coronary artery disease undergo multivessel or culprit-only stenting …

…, MS Lauer, IM Singh, DP Chew, J Karha… - Journal of the American …, 2007 - jacc.org
Objectives : We examined the safety and efficacy of nonculprit multivessel compared with
culprit-only stenting in patients with multivessel disease presenting with unstable angina or non…

[HTML][HTML] Bioprosthetic valve fracture: technical insights from a multicenter study

…, V Babaliaros, A Greenbaum, W O'Neill, J Karha… - The Journal of Thoracic …, 2019 - Elsevier
Objective Valve-in-valve transcatheter aortic valve replacement (VIV TAVR) can result in high
residual gradients that are associated with increased mortality. Bioprosthetic valve fracture …

Evaluation of the association of proximal coronary culprit artery lesion location with clinical outcomes in acute myocardial infarction

J Karha, SA Murphy, AJ Kirtane, JA de Lemos… - The American journal of …, 2003 - Elsevier
Impaired coronary artery blood flow and left anterior descending (LAD) artery culprit
location are angiographic variables that have been associated with poorer outcomes after …

Development of coronary aneurysm after drug-eluting stent implantation

AA Bavry, JH Chiu, BK Jefferson, J Karha… - Annals of internal …, 2007 - acpjournals.org
Background: The problem of drug-eluting stents increasing the risk for late thrombosis,
especially when antiplatelet therapy becomes interupted, is a growing concern (1). Recently, a …

Safety and efficacy of tenecteplase in acute myocardial infarction

DR Guerra, J Karha, CM Gibson - Expert opinion on …, 2003 - Taylor & Francis
The use of intravenous thrombolytic agents has revolutionised the treatment of acute myocardial
infarction. However, the improved mortality achieved with these drugs is tempered by …

Lack of effect of enteric coating on aspirin-induced inhibition of platelet aggregation in healthy volunteers

J Karha, V Rajagopal, K Kottke-Marchant… - American heart journal, 2006 - Elsevier
BACKGROUND: Aspirin inhibits platelet aggregation and is widely used in the treatment of
cardiovascular disease. Some individuals are less responsive to aspirin's antiplatelet effect, a …

Distance from the coronary ostium to the culprit lesion in acute ST-elevation myocardial infarction and its implications regarding the potential prevention of proximal …

CM Gibson, AJ Kirtane, SA Murphy, J Karha… - Journal of thrombosis …, 2003 - Springer
Background: Shorter distances from the coronary ostia to culprit lesions have been associated
with a higher incidence of adverse outcomes in ST elevation acute myocardial infarction (…

Presence of carotid and peripheral arterial disease in patients with left main disease

AL Doonan, J Karha, TP Carrigan, AA Bavry… - The American journal of …, 2007 - Elsevier
Left main (LM) coronary disease, carotid artery disease, and peripheral arterial disease each
reflects advanced atherosclerosis. The frequency of their coexistence in the same patient …