Very few genetic variants have been associated with depression and neuroticism, likely
because of limitations on sample size in previous studies. Subjective well-being, a phenotype …

In the vast majority of cardiovascular diseases (CVDs), there are well-described differences
between women and men in epidemiology, pathophysiology, clinical manifestations, effects …

Aim: Gender differences in morbidity have been widely confirmed in representative health
surveys in North America and Europe. Significantly more women than men suffer from somatic …

Multimorbidity is a common problem in aged populations with a wide range of individual and
societal consequences. The objective of the study was to explore patterns of comorbidity …

… specialist researcher19, Karl-Heinz Jöckel professor20, France Kittel professor of health …
of epidemiology4, Karl-Heinz Ladwig professor of psychosomatic medicine22, Thorsten …

Background Job strain is associated with an increased coronary heart disease risk, but few
large-scale studies have examined the relationship of this psychosocial characteristic with …

Context Cardiac disease and treatment with an implantable cardioverter-defibrillator (ICD)
may be psychologically traumatic. Posttraumatic stress disorder (PTSD) is generally …

BACKGROUND: Depression is a heritable trait that exists on a continuum of varying severity
and duration. Yet, the search for genetic variants associated with depression has had few …

Aging and psychosocial stress are associated with increased inflammation and disease risk,
but the underlying molecular mechanisms are unclear. Because both aging and stress are …

In Germany, large, population-based cohort studies have been implemented in order to identify
risk and protective factors for maintaining health across the life span. The purpose of this …