The Fas ligand is predominantly expressed in activated T lymphocytes and is one of the major
effector molecules of cytotoxic T lymphocytes and natural killer cells. Previously, we found …

Ferroptosis is a necrotic form of regulated cell death (RCD) mediated by phospholipid
peroxidation in association with free iron-mediated Fenton reactions. Disrupted iron homeostasis …

Programmed cell death ligand-1 (PD-L1) has recently gained considerable attention for its
role in tumor immune escape. Here, we identify a miR-197/CKS1B/STAT3-mediated PD-L1 …

Extracellular vesicles (EVs), such as exosomes and microvesicles, encapsulate proteins
and microRNAs (miRNAs) as new modulators of both intercellular crosstalk and disease …

Increasing attention is being paid to the role of extracellular vesicles (EVs) in various lung
diseases. EVs are released by a variety of cells, including respiratory cells and immune cells, …

Background Biomarkers for predicting the effect of anti–programmed cell death 1 (PD-1)
monoclonal antibody against non–small-cell lung cancer (NSCLC) are urgently required. …

Aberrant epithelial–mesenchymal interactions have critical roles in regulating fibrosis
development. The involvement of extracellular vesicles (EVs), including exosomes, remains to be …

The purpose of this study was to compare the dimensions of the peripheral airways in fatal
asthma with those from patients with nonfatal asthma, mild COPD, and normal lung function. …

The tumor suppressor p53 protein is a transcription factor that plays a central role in the
cellular response to DNA damage, and it can cause either G1 arrest or apoptosis. Recently, it …

Background Postoperative pulmonary complications (PPC) in patients with pulmonary diseases
remain to be resolved clinical issue. However, most evidence regarding PPC has been …