Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury

KR McCurry, DL Kooyman, CG Alvarado… - Nature medicine, 1995 - nature.com
The susceptibility of xenografts to hyperacute rejection is postulated to reflect in part failure
of complement regulatory proteins (CRPs) to control activation of heterologous complement …

Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti-inflammatory and anti-apoptotic effects

…, W Ning, TD Oury, PJ Lee, KR McCurry… - The American journal of …, 2003 - Elsevier
Successful lung transplantation has been limited by the high incidence of acute graft rejection.
There is mounting evidence that the stress response gene heme oxygenase-1 (HO-1) and/…

Transgenic pigs expressing human CD59 and decay-accelerating factor produce an intrinsic barrier to complement-mediated damage1

GW Byrne, KR McCurry, MJ Martin, SM McClellan… - …, 1997 - journals.lww.com
We characterize a line of transgenic pigs that express the human complement-regulatory
proteins human CD59 and human decay-accelerating factor. These genes, under the control of …

Opportunistic infections in 547 organ transplant recipients receiving alemtuzumab, a humanized monoclonal CD-52 antibody

…, N Thai, K Abu-Elmagd, KR McCurry… - Clinical infectious …, 2007 - academic.oup.com
Background . Alemtuzumab is being increasingly used for the prevention and/or treatment of
acute allograft rejection in organ transplant recipients. We assessed the risks of infection in, …

[HTML][HTML] Oral hydrogen water prevents chronic allograft nephropathy in rats

…, J Zhan, Y Wang, R Sugimoto, A Tsung, KR McCurry… - Kidney International, 2010 - Elsevier
Reactive oxygen species (ROS) contribute to the development of interstitial fibrosis and tubular
atrophy seen in chronic allograft nephropathy (CAN). As molecular hydrogen gas can act …

[HTML][HTML] A randomized trial of inhaled cyclosporine in lung-transplant recipients

…, JJ Fung, GJ Burckart, KR McCurry… - … England Journal of …, 2006 - Mass Medical Soc
Background Conventional regimens of immunosuppressive drugs often do not prevent
chronic rejection after lung transplantation. Topical delivery of cyclosporine in addition to …

[HTML][HTML] Prospective assessment of Platelia™ Aspergillus galactomannan antigen for the diagnosis of invasive aspergillosis in lung transplant recipients

…, MM Wagener, S Kusne, JE Stout, KR McCurry… - American Journal of …, 2004 - Elsevier
The clinical utility of Platelia™Aspergillus galactomannan antigen for the early diagnosis of
invasive aspergillosis was prospectively assessed in 70 consecutive lung transplant …

Lung transplantation in scleroderma compared with idiopathic pulmonary fibrosis and idiopathic pulmonary arterial hypertension

…, JV Conte, SC Yang, KR McCurry… - … : Official Journal of …, 2006 - Wiley Online Library
Objective Lung transplantation is a viable, life‐saving intervention for several primary
pulmonary disorders complicated by severe lung dysfunction. This study was undertaken to …

Aspergillus galactomannan antigen in the bronchoalveolar lavage fluid for the diagnosis of invasive aspergillosis in lung transplant recipients

…, L McLaughlin, C Bentsen, KR McCurry… - …, 2007 - journals.lww.com
Background. The clinical utility of Platelia Aspergillus enzyme immunoassay (EIA) for
galactomannan (GM) antigen detection in bronchoalveolar lavage (BAL) for the diagnosis of …

Therapeutic antioxidant medical gas

…, R Sugimoto, TR Billiar, KR McCurry - Journal of clinical …, 2009 - jstage.jst.go.jp
Medical gases are pharmaceutical gaseous molecules which offer solutions to medical
needs and include traditional gases, such as oxygen and nitrous oxide, as well as gases with …