Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
…, V Andersen, JM Andrews, L Baidoo… - Nature, 2012 - nature.com
Crohn’s disease and ulcerative colitis, the two common forms of inflammatory bowel disease
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
…, R Scott, L Amininejad, S Bumpstead, L Baidoo… - Nature …, 2011 - nature.com
Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…
Infliximab prevents Crohn's disease recurrence after ileal resection
M Regueiro, W Schraut, L Baidoo, KE Kip… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Crohn's disease commonly recurs after intestinal resection. We
evaluated whether the administration of infliximab after resective intestinal surgery for Crohn's …
evaluated whether the administration of infliximab after resective intestinal surgery for Crohn's …
[HTML][HTML] Appropriate therapeutic drug monitoring of biologic agents for patients with inflammatory bowel diseases
…, NV Casteele, PL Kozuch, LE Raffals, L Baidoo… - Clinical …, 2019 - Elsevier
Background & Aims Therapeutic drug monitoring (TDM) is widely available for biologic
therapies in patients with inflammatory bowel disease (IBD). We reviewed current data and …
therapies in patients with inflammatory bowel disease (IBD). We reviewed current data and …
Association of vitamin D level with clinical status in inflammatory bowel disease: a 5-year longitudinal study
…, M Schwartz, JG Hashash, L Baidoo… - Official journal of the …, 2016 - journals.lww.com
OBJECTIVES: Emerging data suggest that vitamin D has a significant role in inflammatory
bowel disease (IBD). Prospective data evaluating the association of vitamin D serum status …
bowel disease (IBD). Prospective data evaluating the association of vitamin D serum status …
Impact of obesity on the management and clinical course of patients with inflammatory bowel disease
…, A Dudekula, M Regueiro, L Baidoo… - Inflammatory bowel …, 2015 - academic.oup.com
Background Obesity has been linked with a proinflammatory state and the development of
inflammatory diseases. Data on the clinical course and treatment of obese patients with …
inflammatory diseases. Data on the clinical course and treatment of obese patients with …
Geriatric inflammatory bowel disease: phenotypic presentation, treatment patterns, nutritional status, outcomes, and comorbidity
M Juneja, L Baidoo, MB Schwartz, A Barrie… - Digestive diseases and …, 2012 - Springer
Background and Aims The US population is aging and the burden of geriatric inflammatory
bowel disease (IBD) patients has increased. Systematic data describing phenotypic …
bowel disease (IBD) patients has increased. Systematic data describing phenotypic …
Crohn's disease activity index does not correlate with endoscopic recurrence one year after ileocolonic resection
M Regueiro, KE Kip, W Schraut, L Baidoo… - Inflammatory bowel …, 2011 - academic.oup.com
Background Crohn's disease clinical trials utilize the Crohn's Disease Activity Index (CDAI)
to measure primary endpoint assessments of clinical recurrence and remission. We …
to measure primary endpoint assessments of clinical recurrence and remission. We …
Postoperative therapy with infliximab prevents long-term Crohn's disease recurrence
Background & Aims A previous randomized, placebo-controlled study showed that infliximab
maintenance therapy prevented recurrence of Crohn’s disease 1 year after an ileocolonic …
maintenance therapy prevented recurrence of Crohn’s disease 1 year after an ileocolonic …
A pleiotropic missense variant in SLC39A8 is associated with Crohn's disease and human gut microbiome composition
…, L Klei, A Ananthakrishnan, G Aumais, L Baidoo… - Gastroenterology, 2016 - Elsevier
Background & Aims Genome-wide association studies have identified 200 inflammatory
bowel disease (IBD) loci, but the genetic architecture of Crohn’s disease (CD) and ulcerative …
bowel disease (IBD) loci, but the genetic architecture of Crohn’s disease (CD) and ulcerative …