Background Each year, clinical upper gastrointestinal events occur in 2 to 4 percent of patients
who are taking nonselective nonsteroidal antiinflammatory drugs (NSAIDs). We assessed …

Background Gastrointestinal complications are an important problem of antithrombotic
therapy. Proton-pump inhibitors (PPIs) are believed to decrease the risk of such complications, …

Endoscopic hemostatic therapy for upper gastrointestinal bleeding is gaining widespread
acceptance despite often conflicting results of randomized controlled trials. To examine the …

Background Ozanimod, a selective sphingosine-1-phosphate receptor modulator, is under
investigation for the treatment of inflammatory bowel disease. Methods We conducted a …

Peptic ulcer is the most common cause of acute hemorrhage in the upper gastrointestinal
tract, accounting for about 50 percent of cases 1 – 14 . There are approximately 150,000 …

The gastric mucosa maintains structural integrity and function despite continuous exposure
to noxious factors, including 0.1 mol/L HCl and pepsin, that are capable of digesting tissue. …

This guideline presents recommendations for the step-wise management of patients with
overt upper gastrointestinal bleeding. Hemodynamic status is first assessed, and resuscitation …

Purpose: To compare the effect of endoscopic ligation with that of sclerotherapy in the
treatment of patients with bleeding esophageal varices. Data Sources: Strategies to identify …

To avoid actual, potential, or perceived conflicts of interest that may arise as a result of
industry relationships or personal interests among the writing committee, all members of the …

Patients with ulcerative colitis or Crohn’s colitis have an increased risk of colorectal cancer (CRC).
Most cases are believed to arise from dysplasia, and surveillance colonoscopy …