User profiles for Mark E. Dunlap

Mark E. Dunlap

Professor of Medicine, Physiology and of Biophysics, Case Western Reserve University
Verified email at metrohealth.org
Cited by 6650

[HTML][HTML] Effect of nesiritide in patients with acute decompensated heart failure

…, LI Deckelbaum, R Diaz, ME Dunlap… - … England Journal of …, 2011 - Mass Medical Soc
Background Nesiritide is approved in the United States for early relief of dyspnea in patients
with acute heart failure. Previous meta-analyses have raised questions regarding renal …

Mortality and morbidity reduction with Candesartan in patients with chronic heart failure and left ventricular systolic dysfunction: results of the CHARM low-left …

JB Young, ME Dunlap, MA Pfeffer, JL Probstfield… - Circulation, 2004 - Am Heart Assoc
Background— Patients with symptomatic chronic heart failure (CHF) and reduced left
ventricular ejection fraction (LVEF) have a high risk of death and hospitalization for CHF …

Effects of xanthine oxidase inhibition in hyperuricemic heart failure patients: the xanthine oxidase inhibition for hyperuricemic heart failure patients (EXACT-HF) study

…, H Haddad, J Butler, WHW Tang, ME Dunlap… - Circulation, 2015 - Am Heart Assoc
Background— Oxidative stress may contribute to heart failure (HF) progression. Inhibiting
xanthine oxidase in hyperuricemic HF patients may improve outcomes. Methods and Results…

Characterization of health‐related quality of life in heart failure patients with preserved versus low ejection fraction in CHARM

…, E O'Meara, CB Granger, ME Dunlap… - European journal of …, 2007 - Wiley Online Library
Background: Limited comparative studies assessing the health‐related quality of life (HRQL)
in heart failure (HF) patients with preserved vs. low ejection fraction (LVEF) have been …

Sympathetically mediated changes in capacitance: redistribution of the venous reservoir as a cause of decompensation

C Fallick, PA Sobotka, ME Dunlap - Circulation: Heart Failure, 2011 - Am Heart Assoc
“A 57-year-old patient with a history of heart failure states that she began experiencing
worsening shortness of breath 4 days prior to admission, with lower extremity edema developing …

Effect of treatment with sacubitril/valsartan in patients with advanced heart failure and reduced ejection fraction: a randomized clinical trial

…, N Norton, J Nichols, P Leo, ME Dunlap… - JAMA …, 2022 - jamanetwork.com
Importance The use of sacubitril/valsartan is not endorsed by practice guidelines for use in
patients with New York Heart Association class IV heart failure with a reduced ejection …

6-min walk test provides prognostic utility comparable to cardiopulmonary exercise testing in ambulatory outpatients with systolic heart failure

…, RS McKelvie, RM Clare, SJ Ellis, ME Dunlap… - Journal of the American …, 2012 - jacc.org
Objectives : The goal of this study was to compare the prognostic efficacy of the 6-min walk (6MW)
and cardiopulmonary exercise (CPX) tests in stable outpatients with chronic heart …

Pulsatile hemodynamics in congestive heart failure

…, JMO Arnold, G Marchiori, TX O'Brien, ME Dunlap… - …, 2001 - Am Heart Assoc
Pulse pressure, an indirect measure of vascular stiffness and pulsatile load, predicts clinical
events in congestive heart failure (CHF), suggesting that abnormal pulsatile load may …

Aortic diameter, wall stiffness, and wave reflection in systolic hypertension

GF Mitchell, PR Conlin, ME Dunlap, Y Lacourciere… - …, 2008 - Am Heart Assoc
Systolic hypertension is associated with increased pulse pressure (PP) and increased risk
for adverse cardiovascular outcomes. However the pathogenesis of increased PP remains …

Incidence and predictors of hyperkalemia in patients with heart failure: an analysis of the CHARM Program

…, CB Granger, S Yusuf, JB Young, ME Dunlap… - Journal of the American …, 2007 - jacc.org
Objectives : We explored the incidence and predictors of hyperkalemia in a broad population
of heart failure patients. Background : When used in optimal doses to treat patients with …