GADD45 is a ubiquitously expressed mammalian gene that is induced by DNA damage and
certain other stresses. Like another p53-regulated gene, p21 WAF1/CIP1 , whose product …

Recently Gadd45, a p53-regulated stress protein, has been implicated in the activation of a
G2/M checkpoint after damage by UV radiation and alkylating agents. While inhibitory …

The possibility that appropriately designed chemotherapy could act selectively against p53-defective
tumor cells was explored in MCF-7 human breast cancer cells. These cells were …

Human cells lacking functional p53 exhibit a partial deficiency in nucleotide excision repair (NER),
the pathway for repair of UV-induced DNA damage. The global genomic repair (GGR) …

Rayleigh's principle is combined with Backus' harmonic tensor decomposition to investigate
the effect of a small anisotropy on the propagation of Love and Rayleigh surface waves in …

The tumor suppressor p53 plays a central role in the cellular responses to genotoxic stress.
Besides its well known role in activation of the G1 checkpoint after exposure to agents like …

The cancer chemopreventive properties of selenium compounds are well documented, yet
little is known of the mechanism(s) by which these agents inhibit carcinogenesis. We show …

We have extended our calculation of the theoretical period of the Chandler wobble to account
for the non-hydrostatic portion of the Earth's equatorial bulge and the effect of the fluid core …

Resonant Ultrasound Spectroscopy (RUS) uses normal modes of elastic bodies to infer material
properties such as elastic moduli and Q. In principle, the complete elastic tensor can be …

The regulation of DNA excision repair pathways by p53 and its downstream genes is an
emerging body of literature, largely distinct and separable from the more-studied cell cycle …