User profiles for Mary E. Lacy

Mary E. Lacy

Assistant Professor of Epidemiology, University of Kentucky
Verified email at uky.edu
Cited by 699

Association of sickle cell trait with hemoglobin A1c in African Americans

ME Lacy, GA Wellenius, AE Sumner, A Correa… - Jama, 2017 - jamanetwork.com
Importance Hemoglobin A 1c (HbA 1c ) reflects past glucose concentrations, but this relationship
may differ between those with sickle cell trait (SCT) and those without it. Objective To …

Reactivation of L1 retrotransposon by benzo (a) pyrene involves complex genetic and epigenetic regulation

…, DE Montoya-Durango, JL Quertermous, ME Lacy… - Epigenetics, 2011 - Taylor & Francis
Benzo(a)pyrene (BaP), is an environmental pollutant present in tobacco smoke and a byproduct
of fossil fuel combustion which likely contributes to the tumorigenic processes in human …

Severe hypoglycemia and cognitive function in older adults with type 1 diabetes: the study of longevity in diabetes (SOLID)

ME Lacy, P Gilsanz, C Eng, MS Beeri, AJ Karter… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE In children with type 1 diabetes (T1D), severe hypoglycemia (SH) is associated
with poorer cognition, but the association of SH with cognitive function in late life is unknown…

High-sensitivity C-reactive protein is associated with incident type 2 diabetes among African Americans: the Jackson Heart Study

VS Effoe, A Correa, H Chen, ME Lacy… - Diabetes …, 2015 - Am Diabetes Assoc
OBJECTIVE Previous studies on the association between hs-CRP and incident type 2
diabetes among African Americans have been inconclusive. We examined the association …

Epigenetic control of mammalian LINE-1 retrotransposon by retinoblastoma proteins

…, Y Liu, I Teneng, T Kalbfleisch, ME Lacy… - Mutation Research …, 2009 - Elsevier
Long interspersed nuclear elements (LINEs or L1 elements) are targeted for epigenetic
silencing during early embryonic development and remain inactive in most cells and tissues. …

Long-term glycemic control and dementia risk in type 1 diabetes

ME Lacy, P Gilsanz, AJ Karter, CP Quesenberry… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE Individuals with type 1 diabetes have experienced an increase in life expectancy,
yet it is unknown what level of glycemic control is ideal for maintaining late-life brain health…

[HTML][HTML] Prediction of incident diabetes in the Jackson Heart Study using high-dimensional machine learning

R Casanova, S Saldana, SL Simpson, ME Lacy… - PloS one, 2016 - journals.plos.org
Statistical models to predict incident diabetes are often based on limited variables. Here we
pursued two main goals: 1) investigate the relative performance of a machine learning …

ACR Appropriateness Criteria® head trauma: 2021 update

…, JS Broder, S Chakraborty, AT Kendi, ME Lacy… - Journal of the American …, 2021 - Elsevier
Head trauma (ie, head injury) is a significant public health concern and is a leading cause of
morbidity and mortality in children and young adults. Neuroimaging plays an important role …

Comparison of cognitive function in older adults with type 1 diabetes, type 2 diabetes, and no diabetes: results from the Study of Longevity in Diabetes (SOLID)

ME Lacy, C Moran, P Gilsanz, MS Beeri… - BMJ Open Diabetes …, 2022 - drc.bmj.com
Introduction The incidence of both type 1 diabetes (T1D) and type 2 diabetes (T2D) is increasing.
Life expectancy is improving in T1D, resulting in a growing population of elderly adults …

Association of type 1 diabetes and hypoglycemic and hyperglycemic events and risk of dementia

…, P Gilsanz, CP Quesenberry, AJ Karter, ME Lacy - Neurology, 2021 - AAN Enterprises
Objective To determine whether severe hypoglycemic and hyperglycemic events are
associated with longitudinal dementia risk in older adults with type 1 diabetes. Methods A …