Aberrant DNA methylation status of endometriosis: epigenetics as the pathogenesis, biomarker and therapeutic target

…, Y Kawano, Y Tsukamoto, M Takano… - Journal of Obstetrics …, 2011 - Wiley Online Library
Endometriosis, a common, benign, estrogen‐dependent disease affecting 3–10% of women
of reproductive age, is characterized by the ectopic growth of endometrial tissue that is …

Accumulation of aberrant CpG hypermethylation by Helicobacter pylori infection promotes development and progression of gastric MALT lymphoma

…, Y Shinnou, K Washio, M Takano… - International …, 2009 - spandidos-publications.com
Aberrant DNA hypermethylation is an important mechanism for the inactivation of tumor-related
genes in human tumors. Gastric mucosa-associated lymphoid tissue (MALT) lymphomas …

Poly (D-lactic acid) as a rheological modifier of poly (L-lactic acid): Shear and biaxial extensional flow behavior

H Yamane, K Sasai, M Takano, M Takahashi - Journal of Rheology, 2004 - pubs.aip.org
The effect of addition of a small amount of poly(D-lactic acid) (PDLA) on the melt rheology of
poly(L-lactic acid) (PLLA) was investigated. PDLA added to PLLA produces a …

[HTML][HTML] Multi-step aberrant CpG island hyper-methylation is associated with the progression of adult T–cell Leukemia/Lymphoma

…, Y Shinnou, T Kondo, K Washio, M Takano… - The American journal of …, 2010 - Elsevier
Aberrant CpG island methylation contributes to the pathogenesis of various malignancies.
However, little is known about the association of epigenetic abnormalities with multistep …

[HTML][HTML] Piezo1-pannexin-1-P2X3 axis in odontoblasts and neurons mediates sensory transduction in dentinal sensitivity

…, S Ubaidus, H Kuroda, S Ito, M Takano… - Frontiers in …, 2022 - frontiersin.org
According to the “hydrodynamic theory,” dentinal pain or sensitivity is caused by dentinal
fluid movement following the application of various stimuli to the dentin surface. Recent …

Empagliflozin suppresses the differentiation/maturation of human epicardial preadipocytes and improves paracrine secretome profile

M Takano, H Kondo, T Harada, M Takahashi… - Basic to Translational …, 2023 - jacc.org
Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce epicardial adipose tissue (EAT)
in humans, enhancing cardioprotective effects on heart failure and atrial fibrillation. We …

[HTML][HTML] Countermeasure and opportunistic screening systems for oral cancer

T Morikawa, T Shibahara, M Takano, M Iwamoto… - Oral oncology, 2021 - Elsevier
Objectives Tokyo Dental College started oral cancer screening in cooperation with a local
dental association in 1992. Reveal the usefulness of Countermeasure and Opportunistic …

[HTML][HTML] Detection of fibrotic remodeling of epicardial adipose tissue in patients with atrial fibrillation: imaging approach based on histological observation

Y Ishii, I Abe, S Kira, T Harada, M Takano, T Oniki… - Heart Rhythm O2, 2021 - Elsevier
Background Fibrotic remodeling of epicardial adipose tissue (EAT) is crucial for proinflammatory
atrial myocardial fibrosis, which leads to atrial fibrillation (AF). Objectives We tested the …

Frequency of odontogenic tumors: a single center study of 1089 cases in Japan and literature review

…, K Nakajima, Y Akashi, T Chujo, M Takano… - Head and Neck …, 2022 - Springer
Several attempts have been made to classify odontogenic tumors; however, the need for a
uniform international classification system led the World Health Organization (WHO) to …

[HTML][HTML] Non-invasive early detection of oral cancers using fluorescence visualization with optical instruments

…, T Shibahara, T Nomura, A Katakura, M Takano - Cancers, 2020 - mdpi.com
Simple Summary Oral cancer has a high mortality rate. Then, oral cancer screening is needed
for early detection and treatment. Fluorescence visualization is non-invasive, convenient, …