Mucociliary clearance in the airways.

A Wanner, M Salathé, TG O'Riordan - American journal of …, 1996 - atsjournals.org
The ventilation of the lung ranges between 1,000 and 21,000 liters per 24 hours in humans
depending on body size and physical activity. This exposes the extensive epithelial surface …

Regulation of mammalian ciliary beating

M Salathe - Annu. Rev. Physiol., 2007 - annualreviews.org
Recent advances in our understanding of the structure-function relationship of motile cilia
with the 9 + 2 microtubular arrangement have helped explain some of the mechanisms of …

Adult patients with bronchiectasis: a first look at the US bronchiectasis research registry

…, E Eden, D Griffith, M Knowles, M Metersky, M Salathe… - Chest, 2017 - Elsevier
Objectives We sought to describe the characteristics of adult patients with bronchiectasis
enrolled in the US Bronchiectasis Research Registry (BRR). Methods The BRR is a database …

Chronic electronic cigarette exposure in mice induces features of COPD in a nicotine-dependent manner

…, B Jundi, N Cummins, E Eden, A Grosche, M Salathe… - Thorax, 2016 - thorax.bmj.com
Background The use of electronic (e)-cigarettes is increasing rapidly, but their lung health
effects are not established. Clinical studies examining the potential long-term impact of e-…

Pannexin 1 contributes to ATP release in airway epithelia

…, F Qiu, G Dahl, GE Conner, M Salathe - American journal of …, 2009 - atsjournals.org
ATP is a paracrine regulator of critical airway epithelial cell functions, but the mechanism of
its release is poorly understood. Pannexin (Panx) proteins, related to invertebrate innexins, …

Regulated hydrogen peroxide production by Duox in human airway epithelial cells

R Forteza, M Salathe, F Miot, R Forteza… - American journal of …, 2005 - atsjournals.org
Hydrogen peroxide (H 2 O 2 ) is found in exhaled breath and is produced by airway epithelia.
In addition, H 2 O 2 is a necessary substrate for the airway lactoperoxidase (LPO) anti-…

Lactoperoxidase and human airway host defense

…, MA Cobas, R Forteza, M Salathe… - American journal of …, 2003 - atsjournals.org
The lactoperoxidase (LPO) antibiotic system is a well-characterized component of mammary
and salivary gland secretions. Because LPO has been shown to function in ovine airways, …

Randomized trial of liposomal amikacin for inhalation in nontuberculous mycobacterial lung disease

…, PA Flume, D Dorgan, M Salathe… - American journal of …, 2017 - atsjournals.org
Matthias SalatheMatthias Salathe … Winthrop KL, Eagle G, McGinnis JP, Micioni L, Daley
CL, Ruoss SJ, Addrizzo-Harris DJ, Flume PA, Dorgan DJ, Salathe M, et al. Subgroup analyses …

Quality of Life Questionnaire-Bronchiectasis: final psychometric analyses and determination of minimal important difference scores

AL Quittner, AE O'Donnell, MA Salathe, SA Lewis, X Li… - Thorax, 2015 - thorax.bmj.com
Background The Quality of Life-Bronchiectasis (QOL-B), a self-administered, patient-reported
outcome measure assessing symptoms, functioning and health-related quality of life for …

The lactoperoxidase system functions in bacterial clearance of airways

…, I Lauredo, R Forteza, A Wanner, M Salathe… - American journal of …, 2000 - atsjournals.org
Airway mucus is a complex mixture of secretory products that provides a multifaceted defense
against pulmonary infection. Mucus contains antimicrobial peptides (eg, defensins) and …