User profiles for Michaël R. Laurent

Michaël R. Laurent

University Hospitals Leuven
Verified email at uzleuven.be
Cited by 5967

Estrogens and androgens in skeletal physiology and pathophysiology

M Almeida, MR Laurent, V Dubois… - Physiological …, 2017 - journals.physiology.org
Estrogens and androgens influence the growth and maintenance of the mammalian skeleton
and are responsible for its sexual dimorphism. Estrogen deficiency at menopause or loss of …

Seeking health information online: does Wikipedia matter?

MR Laurent, TJ Vickers - Journal of the American Medical …, 2009 - academic.oup.com
Objective: To determine the significance of the English Wikipedia as a source of online health
information. Design: The authors measured Wikipedia's ranking on general Internet search …

[HTML][HTML] Wikipedia: a key tool for global public health promotion

…, SC Grover, TJ Vickers, B Meskó, MR Laurent - Journal of medical …, 2011 - jmir.org
The Internet has become an important health information resource for patients and the
general public. Wikipedia, a collaboratively written Web-based encyclopedia, has become the …

Sex steroid actions in male bone

D Vanderschueren, MR Laurent, F Claessens… - Endocrine …, 2014 - academic.oup.com
Sex steroids are chief regulators of gender differences in the skeleton, and male gender is
one of the strongest protective factors against osteoporotic fractures. This advantage in bone …

Frailty and mortality in hospitalized older adults with COVID-19: retrospective observational study

…, E Ho, J Frans, A Smismans, MR Laurent - Journal of the American …, 2020 - Elsevier
… Association of age, frailty, and other baseline characteristics with mortality were evaluated
by Spearman r and multiple logistic regression. Survival according to frailty status was …

Low free testosterone is associated with hypogonadal signs and symptoms in men with normal total testosterone

…, SR Pye, TB Ahern, MR Laurent… - The Journal of …, 2016 - academic.oup.com
Context: During aging, total testosterone (TT) declines and SHBG increases, resulting in a
greater decrease in calculated free T (cFT). Currently, guidelines suggest using TT to …

[HTML][HTML] Effects of orthogeriatric care models on outcomes of hip fracture patients: a systematic review and meta-analysis

…, G Mordant, J Dupont, M Dejaeger, MR Laurent… - Calcified Tissue …, 2022 - Springer
Orthogeriatrics is increasingly recommended in the care of hip fracture patients, although
evidence for this model is conflicting or at least limited. Furthermore, there is no conclusive …

Associations between sex steroids and the development of metabolic syndrome: a longitudinal study in European men

…, JD Finn, MK Rutter, MR Laurent… - The Journal of …, 2015 - academic.oup.com
Context: Low testosterone (T) has been associated with incident metabolic syndrome (MetS),
but it remains unclear if this association is independent of sex hormone binding globulin (…

Muscle-bone interactions: From experimental models to the clinic? A critical update

MR Laurent, V Dubois, F Claessens… - Molecular and cellular …, 2016 - Elsevier
Bone is a biomechanical tissue shaped by forces from muscles and gravitation. Simultaneous
bone and muscle decay and dysfunction (osteosarcopenia or sarco-osteoporosis) is seen …

[HTML][HTML] Sex hormone-binding globulin regulation of androgen bioactivity in vivo: validation of the free hormone hypothesis

MR Laurent, GL Hammond, M Blokland, F Jardí… - Scientific reports, 2016 - nature.com
Sex hormone-binding globulin (SHBG) is the high-affinity binding protein for androgens and
estrogens. According to the free hormone hypothesis, SHBG modulates the bioactivity of sex …