Background. We examined the effect on outcome of mild hypothermia (< 36C) upon intensive
care unit (ICU) admission on patient outcome after coronary artery bypass grafting (CABG) …

Conformational changes (ie, dynamic transitions between pairs of conformational states) play
important roles in many chemical and biological processes. Constructing the Markov state …

Uncovering slow collective variables (CVs) of self-assembly dynamics is important to
elucidate its numerous kinetic assembly pathways and drive the design of novel structures for …

Importance Prior observational studies suggest that aspirin use may be associated with
reduced mortality in high-risk hospitalized patients with COVID-19, but aspirin’s efficacy in …

… Natasha Michaels is an employee of Kerr Drug, Inc. At the time of the study, Rebecca
Chater was an employee of Kerr Drug, Inc. The other authors declare no conflicts of interest or …

Mutations in protein phosphatase 2A (PP2A) are connected to intellectual disability and
cancer. It has been hypothesized that these mutations might disrupt the autoinhibition and …

… The application of such knowledge can be critical to a patient’s health, an application that
requires testing and interpretation relative to medication. Pharmacists are the logical …

Background Despite previous research findings on higher risks of stillbirth among pregnant
individuals with SARS-CoV-2 infection, it is unclear whether the gestational timing of viral …

Background Hypercoagulable state contributing to thrombotic complications worsens COVID-19
severity and outcomes, whereas anticoagulation improves outcomes by alleviating …

Study Objective To estimate the prevalence of potential moderate to severe drug–drug
interactions (DDIs) involving nirmatrelvir/ritonavir, identify interacting medications, and evaluate …